Performance of laser fabricated stimulating electrode arrays for a retinal prosthesis in saline

C. W D Dodds, Y. T. Wong, P. J. Byrnes-Preston, Michael Rendl, N H Lovell, Gregg J. Suaning

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

12 Citations (Scopus)

Abstract

Microelectrode arrays for a stimulating retinal prosthesis were fabricated from laser etched platinum (Pt) foil encased in silicone. A total of 12 arrays were fabricated to test performance in saline. Hexagonal arrangements (N=6) with multiple (6) return electrodes, as well as paired electrodes (N=6) with single returns were constructed. Electron microscopy of the electrode's surfaces was performed. Cyclic voltammetry was performed on all electrodes to measure the real surface area. The electrodes were submerged in saline in an incubator and biphasic pulses of ±162 μA and ±280 μA for 400 μs were applied at a rate of 67.1 Hz for 12 weeks. Microscopy and cyclic voltammetry were repeated and changes to the electrode's surfaces were observed both by visual inspection of the micrographs and analysis of the cyclic voltammetry curves. Extensive corrosion to those electrodes subjected to the higher current suggests a charge injection limit of less than the original 350μC/cm 2 estimate. Analysis of different corrosion levels between the hexagonal and paired arrangements show that a hexagonally arranged electrode array, with multiple return electrodes, allows a greater stimulation current to be used without reaching the charge injection limit of the electrodes.

Original languageEnglish
Title of host publication2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09
Pages88-91
Number of pages4
DOIs
Publication statusPublished - 2009
Externally publishedYes
EventInternational IEEE Engineering-in-Medicine-and-Biology-Society (EMBS) Conference on Neural Engineering (NER) 2009 - Antalya, Turkey, Antalya, Turkey
Duration: 29 Apr 20092 May 2009
Conference number: 4th

Conference

ConferenceInternational IEEE Engineering-in-Medicine-and-Biology-Society (EMBS) Conference on Neural Engineering (NER) 2009
Abbreviated titleNER '09
CountryTurkey
CityAntalya
Period29/04/092/05/09

Keywords

  • Microelectrodes
  • Neural interfaces
  • Neural stimulation
  • Vision prosthesis

Cite this

Dodds, C. W. D., Wong, Y. T., Byrnes-Preston, P. J., Rendl, M., Lovell, N. H., & Suaning, G. J. (2009). Performance of laser fabricated stimulating electrode arrays for a retinal prosthesis in saline. In 2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09 (pp. 88-91). [5109241] https://doi.org/10.1109/NER.2009.5109241
Dodds, C. W D ; Wong, Y. T. ; Byrnes-Preston, P. J. ; Rendl, Michael ; Lovell, N H ; Suaning, Gregg J. / Performance of laser fabricated stimulating electrode arrays for a retinal prosthesis in saline. 2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09. 2009. pp. 88-91
@inproceedings{f3906eacbf2243479634951d009dcd5a,
title = "Performance of laser fabricated stimulating electrode arrays for a retinal prosthesis in saline",
abstract = "Microelectrode arrays for a stimulating retinal prosthesis were fabricated from laser etched platinum (Pt) foil encased in silicone. A total of 12 arrays were fabricated to test performance in saline. Hexagonal arrangements (N=6) with multiple (6) return electrodes, as well as paired electrodes (N=6) with single returns were constructed. Electron microscopy of the electrode's surfaces was performed. Cyclic voltammetry was performed on all electrodes to measure the real surface area. The electrodes were submerged in saline in an incubator and biphasic pulses of ±162 μA and ±280 μA for 400 μs were applied at a rate of 67.1 Hz for 12 weeks. Microscopy and cyclic voltammetry were repeated and changes to the electrode's surfaces were observed both by visual inspection of the micrographs and analysis of the cyclic voltammetry curves. Extensive corrosion to those electrodes subjected to the higher current suggests a charge injection limit of less than the original 350μC/cm 2 estimate. Analysis of different corrosion levels between the hexagonal and paired arrangements show that a hexagonally arranged electrode array, with multiple return electrodes, allows a greater stimulation current to be used without reaching the charge injection limit of the electrodes.",
keywords = "Microelectrodes, Neural interfaces, Neural stimulation, Vision prosthesis",
author = "Dodds, {C. W D} and Wong, {Y. T.} and Byrnes-Preston, {P. J.} and Michael Rendl and Lovell, {N H} and Suaning, {Gregg J.}",
year = "2009",
doi = "10.1109/NER.2009.5109241",
language = "English",
isbn = "9781424420735",
pages = "88--91",
booktitle = "2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09",

}

Dodds, CWD, Wong, YT, Byrnes-Preston, PJ, Rendl, M, Lovell, NH & Suaning, GJ 2009, Performance of laser fabricated stimulating electrode arrays for a retinal prosthesis in saline. in 2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09., 5109241, pp. 88-91, International IEEE Engineering-in-Medicine-and-Biology-Society (EMBS) Conference on Neural Engineering (NER) 2009, Antalya, Turkey, 29/04/09. https://doi.org/10.1109/NER.2009.5109241

Performance of laser fabricated stimulating electrode arrays for a retinal prosthesis in saline. / Dodds, C. W D; Wong, Y. T.; Byrnes-Preston, P. J.; Rendl, Michael; Lovell, N H; Suaning, Gregg J.

2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09. 2009. p. 88-91 5109241.

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

TY - GEN

T1 - Performance of laser fabricated stimulating electrode arrays for a retinal prosthesis in saline

AU - Dodds, C. W D

AU - Wong, Y. T.

AU - Byrnes-Preston, P. J.

AU - Rendl, Michael

AU - Lovell, N H

AU - Suaning, Gregg J.

PY - 2009

Y1 - 2009

N2 - Microelectrode arrays for a stimulating retinal prosthesis were fabricated from laser etched platinum (Pt) foil encased in silicone. A total of 12 arrays were fabricated to test performance in saline. Hexagonal arrangements (N=6) with multiple (6) return electrodes, as well as paired electrodes (N=6) with single returns were constructed. Electron microscopy of the electrode's surfaces was performed. Cyclic voltammetry was performed on all electrodes to measure the real surface area. The electrodes were submerged in saline in an incubator and biphasic pulses of ±162 μA and ±280 μA for 400 μs were applied at a rate of 67.1 Hz for 12 weeks. Microscopy and cyclic voltammetry were repeated and changes to the electrode's surfaces were observed both by visual inspection of the micrographs and analysis of the cyclic voltammetry curves. Extensive corrosion to those electrodes subjected to the higher current suggests a charge injection limit of less than the original 350μC/cm 2 estimate. Analysis of different corrosion levels between the hexagonal and paired arrangements show that a hexagonally arranged electrode array, with multiple return electrodes, allows a greater stimulation current to be used without reaching the charge injection limit of the electrodes.

AB - Microelectrode arrays for a stimulating retinal prosthesis were fabricated from laser etched platinum (Pt) foil encased in silicone. A total of 12 arrays were fabricated to test performance in saline. Hexagonal arrangements (N=6) with multiple (6) return electrodes, as well as paired electrodes (N=6) with single returns were constructed. Electron microscopy of the electrode's surfaces was performed. Cyclic voltammetry was performed on all electrodes to measure the real surface area. The electrodes were submerged in saline in an incubator and biphasic pulses of ±162 μA and ±280 μA for 400 μs were applied at a rate of 67.1 Hz for 12 weeks. Microscopy and cyclic voltammetry were repeated and changes to the electrode's surfaces were observed both by visual inspection of the micrographs and analysis of the cyclic voltammetry curves. Extensive corrosion to those electrodes subjected to the higher current suggests a charge injection limit of less than the original 350μC/cm 2 estimate. Analysis of different corrosion levels between the hexagonal and paired arrangements show that a hexagonally arranged electrode array, with multiple return electrodes, allows a greater stimulation current to be used without reaching the charge injection limit of the electrodes.

KW - Microelectrodes

KW - Neural interfaces

KW - Neural stimulation

KW - Vision prosthesis

UR - http://www.scopus.com/inward/record.url?scp=70350215751&partnerID=8YFLogxK

U2 - 10.1109/NER.2009.5109241

DO - 10.1109/NER.2009.5109241

M3 - Conference Paper

SN - 9781424420735

SP - 88

EP - 91

BT - 2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09

ER -

Dodds CWD, Wong YT, Byrnes-Preston PJ, Rendl M, Lovell NH, Suaning GJ. Performance of laser fabricated stimulating electrode arrays for a retinal prosthesis in saline. In 2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09. 2009. p. 88-91. 5109241 https://doi.org/10.1109/NER.2009.5109241