Peeling process in living cell movement under shear flow

Emmanuel Décavé, Daniel Garrivier, Yves Bréchet, Franz Bruckert, Bertrand Fourcade

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Abstract

We present a direct optical observation of the behavior of the contact area between a living cell (Dictyostelium discoideum) and a solid substrate under shear flow. It is shown that the membrane is peeled off the substrate. The relationship between the peeling velocity and the applied force is obtained experimentally and explained from the behavior of individual adhesion bridges. The dissipation occurring during the peeling process is explicitly calculated in terms of out-of-equilibrium thermodynamics.

Original languageEnglish
JournalPhysical Review Letters
Volume89
Issue number10
DOIs
Publication statusPublished - 2002
Externally publishedYes

Cite this