Pdha‐2: A model for studying transcriptional regulation in early spermatocytes

Rocco C. Iannello; Julia C. Young; Ismail Kola

doi:10.1002/mrd.1080390212

Pdha‐2: A model for studying transcriptional regulation in early spermatocytes

Rocco C. Iannello, Julia C. Young, Ismail Kola

Research output: Contribution to journal › Review Article › Research › peer-review

3 Citations (Scopus)

Abstract

Precise temporal and tissue‐specific expression of genes during spermatocyte differentiation is crucial for the formation of functional spermatozoa. However, the mechanisms that regulate gene expression during spermatogenesis are poorly understood. One testisspecific gene, Pdha‐2, is beginning to emerge as a potentially important model for the study of these events. This review focuses on our current understanding of the expression and regulation of Pdha‐2 during spermatogenesis. © 1994 Wiley‐Liss, Inc.

Original language	English
Pages (from-to)	194-199
Number of pages	6
Journal	Molecular Reproduction and Development
Volume	39
Issue number	2
DOIs	https://doi.org/10.1002/mrd.1080390212
Publication status	Published - Oct 1994
Externally published	Yes

Keywords

MEP‐BF
Mouse
Pdha‐2 Promoter
Spermatogenesis
Transcription factors

Access to Document

10.1002/mrd.1080390212

Link to publication in Scopus

Cite this

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title = "Pdha‐2: A model for studying transcriptional regulation in early spermatocytes",

abstract = "Precise temporal and tissue‐specific expression of genes during spermatocyte differentiation is crucial for the formation of functional spermatozoa. However, the mechanisms that regulate gene expression during spermatogenesis are poorly understood. One testisspecific gene, Pdha‐2, is beginning to emerge as a potentially important model for the study of these events. This review focuses on our current understanding of the expression and regulation of Pdha‐2 during spermatogenesis. {\textcopyright} 1994 Wiley‐Liss, Inc.",

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AB - Precise temporal and tissue‐specific expression of genes during spermatocyte differentiation is crucial for the formation of functional spermatozoa. However, the mechanisms that regulate gene expression during spermatogenesis are poorly understood. One testisspecific gene, Pdha‐2, is beginning to emerge as a potentially important model for the study of these events. This review focuses on our current understanding of the expression and regulation of Pdha‐2 during spermatogenesis. © 1994 Wiley‐Liss, Inc.

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KW - Pdha‐2 Promoter

KW - Spermatogenesis

KW - Transcription factors

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