Patterned chemisorption of proteins by thin polymer film dewetting

Say Kwang Lim, Sebastien Perrier, Chiara Neto

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Abstract

The covalent attachment of proteins and their patterning on surfaces are important in the bio-medical industry, for use in applications such as bio-sensing and biocompatible medical devices. In this work, proteins are chemisorbed by reaction of their amine groups to glutaraldehyde- and carboxylic acid-functionalised surfaces, within patterns obtained by the dewetting of thin polystyrene films. The proof of principle is shown that consecutive attachment of proteins within the same pattern is possible using this method.

Original languageEnglish
Pages (from-to)2598-2602
Number of pages5
JournalSoft Matter
Volume9
Issue number9
DOIs
Publication statusPublished - 5 Mar 2013
Externally publishedYes

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