Pattern of activin A and follistatin release in a sheep model of cardiopulmonary bypass

Yi Chen, David James Phillips, James McMillan, Penny Bedford, Jacob Goldstein, Hui Wu, Mark Hedger, Julian Smith

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Abstract

Activin A, a member of transforming growth factor-I? superfamily, has been established as a critical cytokine released early in endotoxemia and other inflammatory syndromes. The release of activin A and its binding protein, follistatin during cardiopulmonary bypass (CPB) has not been previously reported. Our study aimed to define the pattern of activin A and follistatin release in a sheep CPB model.
Original languageEnglish
Pages (from-to)154 - 160
Number of pages7
JournalCytokine
Volume54
Issue number2
DOIs
Publication statusPublished - 2011

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