Particulate Matter and Hospital Admissions for Stroke in Beijing, China

Modification Effects by Ambient Temperature

Fangfang Huang, Yanxia Luo, Yuming Guo, Lixin Tao, Qin Xu, Chao Wang, Anxin Wang, Xia Li, Jin Guo, Aoshuang Yan, Xiuhua Guo

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Abstract

BACKGROUND: The impact of particulate matter (PM) on stroke may vary by particle size, stroke subtype, and patient characteristics and temperature. We examined the association of stroke admissions with PM in different subgroups in Beijing, China, during 2013-2014.

METHODS AND RESULTS: A time-stratified case-crossover design was used to assess the relation between PM of different particle sizes and hospital admissions for ischemic and hemorrhagic stroke. Stratified analyses were performed by age, sex, and temperature. In total, there were 147 624 stroke admissions during the study period. In the whole-period analysis, both PM2.5 and PM10 were positively associated with ischemic stroke admissions on the day of hospital admission and negatively associated with ischemic stroke at lag2 and lag3 day. In warm days (>13.5°C), the odds ratios of ischemic stroke admissions were 2.071 (95% CI 1.959-2.190), 1.470 (95% CI 1.391-1.554), and 1.590 (95% CI 1.493-1.694) per IQR increase in the same-day PM2.5 (82.0 μg/m(3)), PM2.5-10 (36.6 μg/m(3)), and PM10 (93.5 μg/m(3)), respectively. For hemorrhagic stroke, the corresponding values were 1.941 (95% CI 1.658-2.273), 1.590 (95% CI 1.366-1.851), and 1.527 (95% CI 1.278-1.826). The positive associations were also observed in the other lag structures and were higher than in cold days (≤13.5°C).

CONCLUSIONS: This study suggests that the associations of PM2.5, PM2.5-10, and PM10 with stroke admissions differed across levels of temperature. Short-term exposure to PM2.5, PM2.5-10, and PM10 was positively associated with hospital admissions for ischemic and hemorrhagic stroke on warm days (>13.5°C).

Original languageEnglish
Article numbere003437
Number of pages11
JournalJournal of the American Heart Association
Volume5
Issue number7
DOIs
Publication statusPublished - 13 Jul 2016
Externally publishedYes

Keywords

  • air pollution
  • hospital admission
  • particulate matter
  • stroke

Cite this

Huang, Fangfang ; Luo, Yanxia ; Guo, Yuming ; Tao, Lixin ; Xu, Qin ; Wang, Chao ; Wang, Anxin ; Li, Xia ; Guo, Jin ; Yan, Aoshuang ; Guo, Xiuhua. / Particulate Matter and Hospital Admissions for Stroke in Beijing, China : Modification Effects by Ambient Temperature. In: Journal of the American Heart Association. 2016 ; Vol. 5, No. 7.
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title = "Particulate Matter and Hospital Admissions for Stroke in Beijing, China: Modification Effects by Ambient Temperature",
abstract = "BACKGROUND: The impact of particulate matter (PM) on stroke may vary by particle size, stroke subtype, and patient characteristics and temperature. We examined the association of stroke admissions with PM in different subgroups in Beijing, China, during 2013-2014.METHODS AND RESULTS: A time-stratified case-crossover design was used to assess the relation between PM of different particle sizes and hospital admissions for ischemic and hemorrhagic stroke. Stratified analyses were performed by age, sex, and temperature. In total, there were 147 624 stroke admissions during the study period. In the whole-period analysis, both PM2.5 and PM10 were positively associated with ischemic stroke admissions on the day of hospital admission and negatively associated with ischemic stroke at lag2 and lag3 day. In warm days (>13.5°C), the odds ratios of ischemic stroke admissions were 2.071 (95{\%} CI 1.959-2.190), 1.470 (95{\%} CI 1.391-1.554), and 1.590 (95{\%} CI 1.493-1.694) per IQR increase in the same-day PM2.5 (82.0 μg/m(3)), PM2.5-10 (36.6 μg/m(3)), and PM10 (93.5 μg/m(3)), respectively. For hemorrhagic stroke, the corresponding values were 1.941 (95{\%} CI 1.658-2.273), 1.590 (95{\%} CI 1.366-1.851), and 1.527 (95{\%} CI 1.278-1.826). The positive associations were also observed in the other lag structures and were higher than in cold days (≤13.5°C).CONCLUSIONS: This study suggests that the associations of PM2.5, PM2.5-10, and PM10 with stroke admissions differed across levels of temperature. Short-term exposure to PM2.5, PM2.5-10, and PM10 was positively associated with hospital admissions for ischemic and hemorrhagic stroke on warm days (>13.5°C).",
keywords = "air pollution, hospital admission, particulate matter, stroke",
author = "Fangfang Huang and Yanxia Luo and Yuming Guo and Lixin Tao and Qin Xu and Chao Wang and Anxin Wang and Xia Li and Jin Guo and Aoshuang Yan and Xiuhua Guo",
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Particulate Matter and Hospital Admissions for Stroke in Beijing, China : Modification Effects by Ambient Temperature. / Huang, Fangfang; Luo, Yanxia; Guo, Yuming; Tao, Lixin; Xu, Qin; Wang, Chao; Wang, Anxin; Li, Xia; Guo, Jin; Yan, Aoshuang; Guo, Xiuhua.

In: Journal of the American Heart Association, Vol. 5, No. 7, e003437, 13.07.2016.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Particulate Matter and Hospital Admissions for Stroke in Beijing, China

T2 - Modification Effects by Ambient Temperature

AU - Huang, Fangfang

AU - Luo, Yanxia

AU - Guo, Yuming

AU - Tao, Lixin

AU - Xu, Qin

AU - Wang, Chao

AU - Wang, Anxin

AU - Li, Xia

AU - Guo, Jin

AU - Yan, Aoshuang

AU - Guo, Xiuhua

PY - 2016/7/13

Y1 - 2016/7/13

N2 - BACKGROUND: The impact of particulate matter (PM) on stroke may vary by particle size, stroke subtype, and patient characteristics and temperature. We examined the association of stroke admissions with PM in different subgroups in Beijing, China, during 2013-2014.METHODS AND RESULTS: A time-stratified case-crossover design was used to assess the relation between PM of different particle sizes and hospital admissions for ischemic and hemorrhagic stroke. Stratified analyses were performed by age, sex, and temperature. In total, there were 147 624 stroke admissions during the study period. In the whole-period analysis, both PM2.5 and PM10 were positively associated with ischemic stroke admissions on the day of hospital admission and negatively associated with ischemic stroke at lag2 and lag3 day. In warm days (>13.5°C), the odds ratios of ischemic stroke admissions were 2.071 (95% CI 1.959-2.190), 1.470 (95% CI 1.391-1.554), and 1.590 (95% CI 1.493-1.694) per IQR increase in the same-day PM2.5 (82.0 μg/m(3)), PM2.5-10 (36.6 μg/m(3)), and PM10 (93.5 μg/m(3)), respectively. For hemorrhagic stroke, the corresponding values were 1.941 (95% CI 1.658-2.273), 1.590 (95% CI 1.366-1.851), and 1.527 (95% CI 1.278-1.826). The positive associations were also observed in the other lag structures and were higher than in cold days (≤13.5°C).CONCLUSIONS: This study suggests that the associations of PM2.5, PM2.5-10, and PM10 with stroke admissions differed across levels of temperature. Short-term exposure to PM2.5, PM2.5-10, and PM10 was positively associated with hospital admissions for ischemic and hemorrhagic stroke on warm days (>13.5°C).

AB - BACKGROUND: The impact of particulate matter (PM) on stroke may vary by particle size, stroke subtype, and patient characteristics and temperature. We examined the association of stroke admissions with PM in different subgroups in Beijing, China, during 2013-2014.METHODS AND RESULTS: A time-stratified case-crossover design was used to assess the relation between PM of different particle sizes and hospital admissions for ischemic and hemorrhagic stroke. Stratified analyses were performed by age, sex, and temperature. In total, there were 147 624 stroke admissions during the study period. In the whole-period analysis, both PM2.5 and PM10 were positively associated with ischemic stroke admissions on the day of hospital admission and negatively associated with ischemic stroke at lag2 and lag3 day. In warm days (>13.5°C), the odds ratios of ischemic stroke admissions were 2.071 (95% CI 1.959-2.190), 1.470 (95% CI 1.391-1.554), and 1.590 (95% CI 1.493-1.694) per IQR increase in the same-day PM2.5 (82.0 μg/m(3)), PM2.5-10 (36.6 μg/m(3)), and PM10 (93.5 μg/m(3)), respectively. For hemorrhagic stroke, the corresponding values were 1.941 (95% CI 1.658-2.273), 1.590 (95% CI 1.366-1.851), and 1.527 (95% CI 1.278-1.826). The positive associations were also observed in the other lag structures and were higher than in cold days (≤13.5°C).CONCLUSIONS: This study suggests that the associations of PM2.5, PM2.5-10, and PM10 with stroke admissions differed across levels of temperature. Short-term exposure to PM2.5, PM2.5-10, and PM10 was positively associated with hospital admissions for ischemic and hemorrhagic stroke on warm days (>13.5°C).

KW - air pollution

KW - hospital admission

KW - particulate matter

KW - stroke

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U2 - 10.1161/JAHA.116.003437

DO - 10.1161/JAHA.116.003437

M3 - Article

VL - 5

JO - American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease

JF - American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease

SN - 2047-9980

IS - 7

M1 - e003437

ER -