Abstract
Nanotubes made from H-bonded cyclic d/l peptide (CP) subunits have great potential for the construction of nanomaterials of wide chemical and structural diversity but, to date, difficulties in structural characterisation have restricted development of these materials. We present the first crystal structures of continuous CP nanotubes with antiparallel and parallel stacking arrangements, assembled separately from two peptides; cyclo[(Asp-d-Leu-Lys-d-Leu)2] and cyclo[(Asp-d-Ala-Lys-d-Ala)2].
| Original language | English |
|---|---|
| Pages (from-to) | 6613-6616 |
| Number of pages | 4 |
| Journal | Chemical Communications |
| Volume | 53 |
| Issue number | 49 |
| DOIs | |
| Publication status | Published - 2017 |
Cite this
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Parallel and antiparallel cyclic d/l peptide nanotubes. / Silk, Mitchell R.; Newman, Janet; Ratcliffe, Julian C.; White, Jacinta F; Caradoc-Davies, Tom; Price, Jason R.; Perrier, Sébastien; Thompson, Philip E.; Chalmers, David K.
In: Chemical Communications, Vol. 53, No. 49, 2017, p. 6613-6616.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Parallel and antiparallel cyclic d/l peptide nanotubes
AU - Silk, Mitchell R.
AU - Newman, Janet
AU - Ratcliffe, Julian C.
AU - White, Jacinta F
AU - Caradoc-Davies, Tom
AU - Price, Jason R.
AU - Perrier, Sébastien
AU - Thompson, Philip E.
AU - Chalmers, David K.
PY - 2017
Y1 - 2017
N2 - Nanotubes made from H-bonded cyclic d/l peptide (CP) subunits have great potential for the construction of nanomaterials of wide chemical and structural diversity but, to date, difficulties in structural characterisation have restricted development of these materials. We present the first crystal structures of continuous CP nanotubes with antiparallel and parallel stacking arrangements, assembled separately from two peptides; cyclo[(Asp-d-Leu-Lys-d-Leu)2] and cyclo[(Asp-d-Ala-Lys-d-Ala)2].
AB - Nanotubes made from H-bonded cyclic d/l peptide (CP) subunits have great potential for the construction of nanomaterials of wide chemical and structural diversity but, to date, difficulties in structural characterisation have restricted development of these materials. We present the first crystal structures of continuous CP nanotubes with antiparallel and parallel stacking arrangements, assembled separately from two peptides; cyclo[(Asp-d-Leu-Lys-d-Leu)2] and cyclo[(Asp-d-Ala-Lys-d-Ala)2].
UR - http://www.scopus.com/inward/record.url?scp=85021709045&partnerID=8YFLogxK
U2 - 10.1039/c7cc00846e
DO - 10.1039/c7cc00846e
M3 - Article
VL - 53
SP - 6613
EP - 6616
JO - Chemical Communications
JF - Chemical Communications
SN - 1359-7345
IS - 49
ER -