Parallel and antiparallel cyclic d/l peptide nanotubes

Mitchell R. Silk, Janet Newman, Julian C. Ratcliffe, Jacinta F White, Tom Caradoc-Davies, Jason R. Price, Sébastien Perrier, Philip E. Thompson, David K. Chalmers

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Abstract

Nanotubes made from H-bonded cyclic d/l peptide (CP) subunits have great potential for the construction of nanomaterials of wide chemical and structural diversity but, to date, difficulties in structural characterisation have restricted development of these materials. We present the first crystal structures of continuous CP nanotubes with antiparallel and parallel stacking arrangements, assembled separately from two peptides; cyclo[(Asp-d-Leu-Lys-d-Leu)2] and cyclo[(Asp-d-Ala-Lys-d-Ala)2].

Original languageEnglish
Pages (from-to)6613-6616
Number of pages4
JournalChemical Communications
Volume53
Issue number49
DOIs
Publication statusPublished - 2017

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