Parallel and antiparallel cyclic d/l peptide nanotubes

Mitchell R. Silk; Janet Newman; Julian C. Ratcliffe; Jacinta F White; Tom Caradoc-Davies; Jason R. Price; Sébastien Perrier; Philip E. Thompson; David K. Chalmers

doi:10.1039/c7cc00846e

Parallel and antiparallel cyclic d/l peptide nanotubes

Mitchell R. Silk, Janet Newman, Julian C. Ratcliffe, Jacinta F White, Tom Caradoc-Davies, Jason R. Price, Sébastien Perrier, Philip E. Thompson, David K. Chalmers

Research output: Contribution to journal › Article › Research › peer-review

15 Citations (Scopus)

Abstract

Nanotubes made from H-bonded cyclic d/l peptide (CP) subunits have great potential for the construction of nanomaterials of wide chemical and structural diversity but, to date, difficulties in structural characterisation have restricted development of these materials. We present the first crystal structures of continuous CP nanotubes with antiparallel and parallel stacking arrangements, assembled separately from two peptides; cyclo[(Asp-d-Leu-Lys-d-Leu)₂] and cyclo[(Asp-d-Ala-Lys-d-Ala)₂].

Original language	English
Pages (from-to)	6613-6616
Number of pages	4
Journal	Chemical Communications
Volume	53
Issue number	49
DOIs	https://doi.org/10.1039/c7cc00846e
Publication status	Published - 2017

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10.1039/c7cc00846e

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Cite this

@article{23574bb576e942e4a7effab3c5f60cab,

title = "Parallel and antiparallel cyclic d/l peptide nanotubes",

abstract = "Nanotubes made from H-bonded cyclic d/l peptide (CP) subunits have great potential for the construction of nanomaterials of wide chemical and structural diversity but, to date, difficulties in structural characterisation have restricted development of these materials. We present the first crystal structures of continuous CP nanotubes with antiparallel and parallel stacking arrangements, assembled separately from two peptides; cyclo[(Asp-d-Leu-Lys-d-Leu)2] and cyclo[(Asp-d-Ala-Lys-d-Ala)2].",

author = "Silk, {Mitchell R.} and Janet Newman and Ratcliffe, {Julian C.} and White, {Jacinta F} and Tom Caradoc-Davies and Price, {Jason R.} and S{\'e}bastien Perrier and Thompson, {Philip E.} and Chalmers, {David K.}",

year = "2017",

doi = "10.1039/c7cc00846e",

language = "English",

volume = "53",

pages = "6613--6616",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "The Royal Society of Chemistry",

number = "49",

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Parallel and antiparallel cyclic d/l peptide nanotubes. / Silk, Mitchell R.; Newman, Janet; Ratcliffe, Julian C.; White, Jacinta F; Caradoc-Davies, Tom; Price, Jason R.; Perrier, Sébastien; Thompson, Philip E.; Chalmers, David K.

In: Chemical Communications, Vol. 53, No. 49, 2017, p. 6613-6616.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Parallel and antiparallel cyclic d/l peptide nanotubes

AU - Silk, Mitchell R.

AU - Newman, Janet

AU - Ratcliffe, Julian C.

AU - White, Jacinta F

AU - Caradoc-Davies, Tom

AU - Price, Jason R.

AU - Perrier, Sébastien

AU - Thompson, Philip E.

AU - Chalmers, David K.

PY - 2017

Y1 - 2017

N2 - Nanotubes made from H-bonded cyclic d/l peptide (CP) subunits have great potential for the construction of nanomaterials of wide chemical and structural diversity but, to date, difficulties in structural characterisation have restricted development of these materials. We present the first crystal structures of continuous CP nanotubes with antiparallel and parallel stacking arrangements, assembled separately from two peptides; cyclo[(Asp-d-Leu-Lys-d-Leu)2] and cyclo[(Asp-d-Ala-Lys-d-Ala)2].

AB - Nanotubes made from H-bonded cyclic d/l peptide (CP) subunits have great potential for the construction of nanomaterials of wide chemical and structural diversity but, to date, difficulties in structural characterisation have restricted development of these materials. We present the first crystal structures of continuous CP nanotubes with antiparallel and parallel stacking arrangements, assembled separately from two peptides; cyclo[(Asp-d-Leu-Lys-d-Leu)2] and cyclo[(Asp-d-Ala-Lys-d-Ala)2].

UR - http://www.scopus.com/inward/record.url?scp=85021709045&partnerID=8YFLogxK

U2 - 10.1039/c7cc00846e

DO - 10.1039/c7cc00846e

M3 - Article

AN - SCOPUS:85021709045

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EP - 6616

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

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