Paper-based sperm DNA integrity analysis

Reza Nosrati; Max M. Gong; Maria C. San Gabriel; Armand Zini; David Sinton

doi:10.1039/c6ay01506a

Paper-based sperm DNA integrity analysis

Reza Nosrati
, Max M. Gong
, Maria C. San Gabriel
, Armand Zini
, David Sinton

Research output: Contribution to journal › Article › Research › peer-review

21 Citations (Scopus)

Abstract

We demonstrate a rapid, sensitive, and low cost paper-based approach for sperm chromatin integrity analysis that quantifies both DNA fragmentation and packaging. The paper-based test provides identical clinical outcome as the gold standard sperm chromatin structure assay. This technology is fast, simple, and suitable for broad application in clinics.

Original language	English
Pages (from-to)	6260-6264
Number of pages	5
Journal	Analytical Methods
Volume	8
Issue number	33
DOIs	https://doi.org/10.1039/c6ay01506a
Publication status	Published - 7 Sept 2016
Externally published	Yes

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title = "Paper-based sperm DNA integrity analysis",

abstract = "We demonstrate a rapid, sensitive, and low cost paper-based approach for sperm chromatin integrity analysis that quantifies both DNA fragmentation and packaging. The paper-based test provides identical clinical outcome as the gold standard sperm chromatin structure assay. This technology is fast, simple, and suitable for broad application in clinics.",

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AU - Nosrati, Reza

AU - Gong, Max M.

AU - San Gabriel, Maria C.

AU - Zini, Armand

AU - Sinton, David

PY - 2016/9/7

Y1 - 2016/9/7

N2 - We demonstrate a rapid, sensitive, and low cost paper-based approach for sperm chromatin integrity analysis that quantifies both DNA fragmentation and packaging. The paper-based test provides identical clinical outcome as the gold standard sperm chromatin structure assay. This technology is fast, simple, and suitable for broad application in clinics.

AB - We demonstrate a rapid, sensitive, and low cost paper-based approach for sperm chromatin integrity analysis that quantifies both DNA fragmentation and packaging. The paper-based test provides identical clinical outcome as the gold standard sperm chromatin structure assay. This technology is fast, simple, and suitable for broad application in clinics.

UR - https://www.scopus.com/pages/publications/84984664060

U2 - 10.1039/c6ay01506a

DO - 10.1039/c6ay01506a

M3 - Article

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SN - 1759-9660

VL - 8

SP - 6260

EP - 6264

JO - Analytical Methods

JF - Analytical Methods

IS - 33

ER -

Paper-based sperm DNA integrity analysis

Abstract

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