Pandangan tentang Aktiviti Antikanser, Fitokimia Berkaitan dan Mekanisme Molekul Berpotensi Quisqualis indica: Suatu Kajian Mini

Translated title of the contribution: Insights on Anticancer Activities, Associated Phytochemicals and Potential Molecular Mechanisms of Quisqualis indica: A Mini Review

Yuan Seng Wu, Michelle Felicia Lee, Rhanye Mac Guad, Fathima Zahraa Ozeer, Appalaraju Velaga, Vetriselvan Subramaniyan, Neeraj Kumar Fuloria, Shivkanya Fuloria, Ker Woon Choy, Sze Meng Lee, Subash C.B. Gopinath, Amita Verma, Tze Pheng Lau

Research output: Contribution to journalReview ArticleResearchpeer-review

1 Citation (Scopus)

Abstract

Drug resistance is the main issue causing the treatment failure of anticancer drugs. This issue has urged researchers to search for new substances from medicinal plants, which are widely reported as the good sources of anticancer agents. Quisqualis indica is a plant belongs to Combretaceae family, known as Rangoon Creeper, which can be found abundantly in tropical countries and distributed profusely as a wild shrub. It has been widely used traditionally and scientifically claimed to process various therapeutic activities. It has recently been reported to possess various potential anticancer activities against different cancers. Looking at its availability in almost all seasons and grow fast, it is an arising source of herbal medicine in the discovery of anticancer drugs economically. Besides, Q. indica is enriched with several secondary metabolites of interest, which are responsible for the positive findings for its anticancer potentials. In this review, we aim to decipher and discuss the anticancer activities of Q. indica crude extracts and isolated phytochemicals as evidenced in preclinical models, as well as the associated molecular mechanisms. More preclinical investigations on its anticancer potentials should be conducted before translation to clinical testing.

Translated title of the contributionInsights on Anticancer Activities, Associated Phytochemicals and Potential Molecular Mechanisms of Quisqualis indica: A Mini Review
Original languageMalay
Pages (from-to)1749-1758
Number of pages10
JournalSains Malaysiana
Volume52
Issue number6
DOIs
Publication statusPublished - Jun 2023

Keywords

  • Anticancer
  • molecular mechanism
  • phytochemicals
  • phytotherapy
  • Quisqualis indica

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