Pan-spinal infection: A case series and review of the literature

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background: Panspinal infection usually presents with fever, back pain, neurological deficit, and in advanced cases multi-organ failure and septic shock. The choice of treatment for panspinal infection is challenging because these patients are usually medically unstable with severe neurological compromise. The objective of this study is to review management and long term outcomes for patients with panspinal infection.

Methods: A retrospective review of patients with panspinal infection treated in our center over a 5-year period [Jan 2010–Dec 2014] and a review of the current published literatures was undertaken.

Results: We identified 4 patients with panspinal infection. One case was managed medically due to high perioperative risk, whilst the other three were managed surgically whilst on antibiotic therapy. All 3 cases managed surgically improved neurologically and infection subsided, whereas the patient managed medically did not change neurologically and infection subsided.

Conclusions: Patients with panspinal infection should be treated surgically unless the medical risk of surgery or anaesthesia is prohibitive.
Original languageEnglish
Pages (from-to)202 - 209
Number of pages8
JournalJournal of Spine Surgery
Volume2
Issue number3
DOIs
Publication statusPublished - Sep 2016

Keywords

  • Panspinal infection
  • holospinal infection
  • epidural infection
  • discitis
  • spinal infection
  • subdural infection

Cite this

@article{d36cdda69615421f897861e1ed2a3fff,
title = "Pan-spinal infection: A case series and review of the literature",
abstract = "Background: Panspinal infection usually presents with fever, back pain, neurological deficit, and in advanced cases multi-organ failure and septic shock. The choice of treatment for panspinal infection is challenging because these patients are usually medically unstable with severe neurological compromise. The objective of this study is to review management and long term outcomes for patients with panspinal infection.Methods: A retrospective review of patients with panspinal infection treated in our center over a 5-year period [Jan 2010–Dec 2014] and a review of the current published literatures was undertaken.Results: We identified 4 patients with panspinal infection. One case was managed medically due to high perioperative risk, whilst the other three were managed surgically whilst on antibiotic therapy. All 3 cases managed surgically improved neurologically and infection subsided, whereas the patient managed medically did not change neurologically and infection subsided.Conclusions: Patients with panspinal infection should be treated surgically unless the medical risk of surgery or anaesthesia is prohibitive.",
keywords = "Panspinal infection, holospinal infection, epidural infection, discitis, spinal infection, subdural infection",
author = "Kow, {Chien Yew} and Patrick Chan and Greg Etherington and Lu Ton and Susan Liew and Cheng, {Allen C.} and Rosenfeld, {Jeffrey V.}",
year = "2016",
month = "9",
doi = "10.21037/jss.2016.08.04",
language = "English",
volume = "2",
pages = "202 -- 209",
journal = "Journal of Spine Surgery",
issn = "2414-469X",
number = "3",

}

Pan-spinal infection : A case series and review of the literature. / Kow, Chien Yew; Chan, Patrick; Etherington, Greg; Ton, Lu; Liew, Susan; Cheng, Allen C.; Rosenfeld, Jeffrey V.

In: Journal of Spine Surgery, Vol. 2, No. 3, 09.2016, p. 202 - 209.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Pan-spinal infection

T2 - A case series and review of the literature

AU - Kow, Chien Yew

AU - Chan, Patrick

AU - Etherington, Greg

AU - Ton, Lu

AU - Liew, Susan

AU - Cheng, Allen C.

AU - Rosenfeld, Jeffrey V.

PY - 2016/9

Y1 - 2016/9

N2 - Background: Panspinal infection usually presents with fever, back pain, neurological deficit, and in advanced cases multi-organ failure and septic shock. The choice of treatment for panspinal infection is challenging because these patients are usually medically unstable with severe neurological compromise. The objective of this study is to review management and long term outcomes for patients with panspinal infection.Methods: A retrospective review of patients with panspinal infection treated in our center over a 5-year period [Jan 2010–Dec 2014] and a review of the current published literatures was undertaken.Results: We identified 4 patients with panspinal infection. One case was managed medically due to high perioperative risk, whilst the other three were managed surgically whilst on antibiotic therapy. All 3 cases managed surgically improved neurologically and infection subsided, whereas the patient managed medically did not change neurologically and infection subsided.Conclusions: Patients with panspinal infection should be treated surgically unless the medical risk of surgery or anaesthesia is prohibitive.

AB - Background: Panspinal infection usually presents with fever, back pain, neurological deficit, and in advanced cases multi-organ failure and septic shock. The choice of treatment for panspinal infection is challenging because these patients are usually medically unstable with severe neurological compromise. The objective of this study is to review management and long term outcomes for patients with panspinal infection.Methods: A retrospective review of patients with panspinal infection treated in our center over a 5-year period [Jan 2010–Dec 2014] and a review of the current published literatures was undertaken.Results: We identified 4 patients with panspinal infection. One case was managed medically due to high perioperative risk, whilst the other three were managed surgically whilst on antibiotic therapy. All 3 cases managed surgically improved neurologically and infection subsided, whereas the patient managed medically did not change neurologically and infection subsided.Conclusions: Patients with panspinal infection should be treated surgically unless the medical risk of surgery or anaesthesia is prohibitive.

KW - Panspinal infection

KW - holospinal infection

KW - epidural infection

KW - discitis

KW - spinal infection

KW - subdural infection

UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067279/

U2 - 10.21037/jss.2016.08.04

DO - 10.21037/jss.2016.08.04

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SP - 202

EP - 209

JO - Journal of Spine Surgery

JF - Journal of Spine Surgery

SN - 2414-469X

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ER -