It is clear that the observable (macroscopic) properties of matter are connected in some, usually complex and non-linear way, with their atomic and molecular (microscopic) properties. The ability to model these relationships is very important in many areas of science, particularly those concerned with the biological properties of molecules. Clearly a single residue change in a peptide sequence, a single atomic change in a small organic molecule, or even a change in the shape of a molecule induced by isomerism can profoundly affect the biological properties of these entities.
|Title of host publication||Molecular Analysis and Genome Discovery|
|Editors||Ralph Rapley, Stuart Harbron|
|Place of Publication||Chichester UK|
|Publisher||John Wiley & Sons|
|Number of pages||21|
|Publication status||Published - 2004|