Osteoporosis prevention and treatment: The importance of vitamin D

Simon Chatfield, Peter R. Ebeling

Research output: Contribution to journalReview ArticleResearchpeer-review

3 Citations (Scopus)


• Even in Australia vitamin D deficiency is common, but it is under-recognised. • Evidence is accumulating that vitamin D supplementation reduces falls and fragility fractures, particularly in groups at risk vitamin D deficiency. The number-needed-to-treat to prevent falls in the elderly is small (n=15). • Assays for 25-hydroxyvitamin D often do not measure vitamin D2 (ergocalciferol) as well as vitamin D3 (cholecalciferol). This makes assessing treatment responses to vitamin D2 supplements difficult. • Vitamin D deficiency should be corrected prior to treatment with intravenous bisphosphonates to avoid hypocalcemia. Low vitamin D levels should also be corrected in patients on oral bisphosphonates. • Calcium supplements will need to be given with vitamin D supplements if patients' dietary calcium intakes are suboptimal. • More studies regarding the role of vitamin D supplementation in the primary prevention of fragility fractures in the elderly are required.

Original languageEnglish
Pages (from-to)16-30
Number of pages15
JournalMedicine Today
Issue number4
Publication statusPublished - 1 Apr 2005
Externally publishedYes

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