Abstract
The collapsin response mediator protein 5 (CRMP-5) autoantibody is one of only several paraneoplastic antibodies associated with autonomic neuropathy. Such paraneoplastic neuropathies manifest with a constellation of autonomic abnormalities. We present a unique case of orthostatic hypotension as the sole feature of a CRMP-5 paraneoplastic autonomic neuropathy in a patient with small cell lung cancer. Given the poor prognosis of paraneoplastic autonomic dysfunction, it is important to accurately diagnose the cause of orthostatic hypotension occurring on a background of malignancy.
Original language | English |
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Pages (from-to) | 885-886 |
Number of pages | 2 |
Journal | Journal of Clinical Neuroscience |
Volume | 21 |
Issue number | 5 |
DOIs | |
Publication status | Published - 1 Jan 2014 |
Externally published | Yes |
Keywords
- Autonomic neuropathy
- CRMP-5
- Orthostatic hypotension
- Paraneoplastic