Organogelation of sheet-helix diblock copolypeptides

Matthew I. Gibson, Neil R. Cameron

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)

Abstract

(Figure Presented) Together they're strong: Block copolypeptides containing poly(benzyl-L-threonine) and an α-helical block are effective organogelators despite the high solubility of the constituent homopolymers. An unexpected conformational change in the first block, from random coil to β sheet, directs the assembly into stacked lamellae (see picture).

Original languageEnglish
Pages (from-to)5160-5162
Number of pages3
JournalAngewandte Chemie - International Edition
Volume47
Issue number28
DOIs
Publication statusPublished - 27 Jun 2008
Externally publishedYes

Keywords

  • Carboxyanhydrides
  • Gels
  • Peptides
  • Polymerization
  • Self-assembly

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