Organocatalytic, regioselective nucleophilic "click" addition of thiols to propiolic acid esters for polyme-polymer coupling

Vinh Xuan Truong, Andrew P Dove

Research output: Contribution to journalArticleResearchpeer-review

63 Citations (Scopus)

Abstract

Discerning Tastes: The regioselectivity of the nucleophilic addition of thiols to electron-deficient alkynes is controlled by the choice of the solvent (i.e. the polarity of the reaction mixture) and the catalyst. Both thioalkenes and dithianes can be prepared in a rapid reaction that generates no by-products (see scheme). In turn the utility of this reaction is shown for efficient end-group modification of polymers
Original languageEnglish
Pages (from-to)4132 - 4136
Number of pages5
JournalAngewandte Chemie - International Edition
Volume52
Issue number15
DOIs
Publication statusPublished - 2013
Externally publishedYes

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