Organic Arsenicals as Functional Motifs in Polymer and Biomaterials Science

Joji Tanaka, Thomas P. Davis, Paul Wilson

Research output: Contribution to journalReview ArticleResearchpeer-review

Abstract

Arsenic (As) exhibits diverse (bio)chemical reactivity and biological activity depending upon its oxidation state. However, this distinctive reactivity has been largely overlooked across many fields owing to concerns regarding the toxicity of arsenic. Recently, a clinical renaissance in the use of arsenicals, including organic arsenicals that are known to be less toxic than inorganic arsenicals, alludes to the possibility of broader acceptance and application in the field of polymer and biomaterials science. Here, current examples of polymeric/macromolecular arsenicals are reported to stimulate interest and highlight their potential as a novel platform for functional, responsive, and bioactive materials.

Original languageEnglish
Article number1800205
Number of pages24
JournalMacromolecular Rapid Communications
Volume39
Issue number19
DOIs
Publication statusPublished - 1 Oct 2018

Keywords

  • biomaterials
  • drug delivery systems
  • imaging
  • nanoparticles
  • polymerization

Cite this

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Organic Arsenicals as Functional Motifs in Polymer and Biomaterials Science. / Tanaka, Joji; Davis, Thomas P.; Wilson, Paul.

In: Macromolecular Rapid Communications, Vol. 39, No. 19, 1800205, 01.10.2018.

Research output: Contribution to journalReview ArticleResearchpeer-review

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AU - Davis, Thomas P.

AU - Wilson, Paul

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AB - Arsenic (As) exhibits diverse (bio)chemical reactivity and biological activity depending upon its oxidation state. However, this distinctive reactivity has been largely overlooked across many fields owing to concerns regarding the toxicity of arsenic. Recently, a clinical renaissance in the use of arsenicals, including organic arsenicals that are known to be less toxic than inorganic arsenicals, alludes to the possibility of broader acceptance and application in the field of polymer and biomaterials science. Here, current examples of polymeric/macromolecular arsenicals are reported to stimulate interest and highlight their potential as a novel platform for functional, responsive, and bioactive materials.

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KW - drug delivery systems

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