Optimization of whispering gallery resonator design for biosensing applications

T. Reynolds, M. R. Henderson, A. François, N. Riesen, J. M.M. Hall, S. V. Afshar, S. J. Nicholls, T. M. Monro

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)


Whispering gallery modes (WGMs) within microsphere cavities enable highly sensitive label-free detection of changes in the surrounding refractive index. This detection modality is of particular interest for biosensing applications. However, the majority of biosensing work utilizing WGMs to date has been conducted with resonators made from either silica or polystyrene, while other materials remain largely uninvestigated. By considering characteristics such as the quality factor and sensitivity of the resonator, the optimal WGM sensor design can be identified for various applications. This work explores the choice of resonator refractive index and size to provide design guidelines for undertaking refractive index biosensing using WGMs.

Original languageEnglish
Pages (from-to)17067-17076
Number of pages10
JournalOptics Express
Issue number13
Publication statusPublished - 29 Jun 2015
Externally publishedYes

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