Optimization of the RAFT polymerization conditions for the in situ formation of nano-objects via dispersion polymerization in alcoholic medium

Wei Zhao; Guillaume Gody; Siming Dong; Per B Zetterlund; Sebastien Paul Edmond Perrier

doi:10.1039/c4py00855c

Optimization of the RAFT polymerization conditions for the in situ formation of nano-objects via dispersion polymerization in alcoholic medium

Wei Zhao, Guillaume Gody, Siming Dong, Per B Zetterlund, Sebastien Paul Edmond Perrier

Drug Delivery Disposition & Dynamics

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101 Citations (Scopus)

Abstract

Hydrophilic polymer brushes based on poly(ethylene glycol) methyl ether acrylate (P(PEGA454)) or poly(ethylene glycol) methyl ether methacrylate (P(PEGMA475)), both having a trithiocarbonate end group, were prepared in water-dioxane (9 : 1) at 44?C via RAFT polymerization, and subsequently used in RAFT dispersion polymerization of styrene in isopropanol at 90?C. RAFT reaction conditions were first optimized to prepare P(PEGA454) and P(PEGMA475) macro-RAFT agents at high monomer conversions (>90 ) and very low fraction of dead chains (

Original language	English
Pages (from-to)	6990 - 7003
Number of pages	14
Journal	Polymer Chemistry
Volume	5
Issue number	24
DOIs	https://doi.org/10.1039/c4py00855c
Publication status	Published - 2014

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10.1039/c4py00855c

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abstract = "Hydrophilic polymer brushes based on poly(ethylene glycol) methyl ether acrylate (P(PEGA454)) or poly(ethylene glycol) methyl ether methacrylate (P(PEGMA475)), both having a trithiocarbonate end group, were prepared in water-dioxane (9 : 1) at 44?C via RAFT polymerization, and subsequently used in RAFT dispersion polymerization of styrene in isopropanol at 90?C. RAFT reaction conditions were first optimized to prepare P(PEGA454) and P(PEGMA475) macro-RAFT agents at high monomer conversions (>90 ) and very low fraction of dead chains (",

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AU - Zhao, Wei

AU - Gody, Guillaume

AU - Dong, Siming

AU - Zetterlund, Per B

AU - Perrier, Sebastien Paul Edmond

PY - 2014

Y1 - 2014

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AB - Hydrophilic polymer brushes based on poly(ethylene glycol) methyl ether acrylate (P(PEGA454)) or poly(ethylene glycol) methyl ether methacrylate (P(PEGMA475)), both having a trithiocarbonate end group, were prepared in water-dioxane (9 : 1) at 44?C via RAFT polymerization, and subsequently used in RAFT dispersion polymerization of styrene in isopropanol at 90?C. RAFT reaction conditions were first optimized to prepare P(PEGA454) and P(PEGMA475) macro-RAFT agents at high monomer conversions (>90 ) and very low fraction of dead chains (

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SP - 6990

EP - 7003

JO - Polymer Chemistry

JF - Polymer Chemistry

IS - 24

ER -

Optimization of the RAFT polymerization conditions for the in situ formation of nano-objects via dispersion polymerization in alcoholic medium

Abstract

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