Pharmacists traditionally play a big role in the provision of healthcare to newborns. They are mothersa?? first port of call for common health conditions in the newborns such as colic, eczema and nappy rash. However, the role of pharmacists in optimizing maternal and fetal health outcomes during pregnancy is not well established. Increasing reliance on pharmacotherapy for maintaining health makes medication exposure in pregnancy inevitable. Prescribing for patients who are pregnant can be a challenge due to insufficient information regarding medication safety and overestimation of perceived risk of medications both by patients and care providers. Safety data on use of medications during pregnancy are limited due to the challenges of conducting well designed clinical trials in this population.Medications such as thalidomide and isotretinoin have clearly been shown to be teratogenic; however, data on foetal effects of most medications are scant. Pregnancy, whether planned or not, brings with it important concerns about the safety of prescription and over the counter medications.