Optical manipulation and fusion of liposomes as microreactors

Simone Kulin; Rani Kishore; Kristian Helmerson; Laurie Locascio

doi:10.1021/la0344433

Optical manipulation and fusion of liposomes as microreactors

Simone Kulin, Rani Kishore, Kristian Helmerson, Laurie Locascio

Research output: Contribution to journal › Article › Research › peer-review

83 Citations (Scopus)

Abstract

We present an all-optical method to manipulate and fuse giant liposomes, typically 10 μm in diameter. Optical tweezers are used to trap two individual liposomes, which are then brought into contact. A single pulse of ultraviolet laser light focused on the adjoining membranes induces the fusion between the liposomes. As a consequence, the chemical reagents encapsulated in the two liposomes mix and a chemical reaction takes place.

Original language	English
Pages (from-to)	8206-8210
Number of pages	5
Journal	Langmuir
Volume	19
Issue number	20
DOIs	https://doi.org/10.1021/la0344433
Publication status	Published - 30 Sep 2003
Externally published	Yes

Access to Document

10.1021/la0344433

Link to publication in Scopus

Cite this

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title = "Optical manipulation and fusion of liposomes as microreactors",

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