Opportunities for ultra-high resolution analysis of essential oils using comprehensive two-dimensional gas chromatography: A review

Robert Shellie, Philip Marriott

Research output: Contribution to journalReview ArticleResearchpeer-review

60 Citations (Scopus)

Abstract

In comprehensive 2D gas chromatography, the entire sample is simultaneously subjected to analysis on two capillary columns. By using a suitable modulation interface between the primary and secondary columns, hundreds of fast, second-dimension chromatograms are produced. The data from these chromatograms are treated such that a 3D surface plot or a 2D contour plot of the components' individual retention times, on each column, as well as peak responses, are represented. In a properly tuned comprehensive 2D chromatogram, the individual sample components are spread throughout a 2D separation space, providing a significant increase in the probability of resolving a greater number of sample components without increasing the analysis time. Comprehensive 2D-GC has proved useful for high-resolution conventional essential oil analysis as well as high-resolution enantioselective essential oil analysis. Combining comprehensive 2D-GC with either a quadrupole or time-of-flight mass spectrometer gives a powerful 3D analysis technique, which is extremely effective for complex sample analysis. The present status and opportunities arising from these ultra-high resolution approaches are discussed herein.

Original languageEnglish
Pages (from-to)179-191
Number of pages13
JournalFlavour and Fragrance Journal
Volume18
Issue number3
DOIs
Publication statusPublished - 1 May 2003
Externally publishedYes

Keywords

  • Comprehensive two-dimensional gas chromatography
  • Enantioselective analysis
  • Essential oils
  • GC x GC
  • High resolution
  • Mass spectrometry

Cite this

@article{acd0fdb95f6646c9b6df172ac46f3e82,
title = "Opportunities for ultra-high resolution analysis of essential oils using comprehensive two-dimensional gas chromatography: A review",
abstract = "In comprehensive 2D gas chromatography, the entire sample is simultaneously subjected to analysis on two capillary columns. By using a suitable modulation interface between the primary and secondary columns, hundreds of fast, second-dimension chromatograms are produced. The data from these chromatograms are treated such that a 3D surface plot or a 2D contour plot of the components' individual retention times, on each column, as well as peak responses, are represented. In a properly tuned comprehensive 2D chromatogram, the individual sample components are spread throughout a 2D separation space, providing a significant increase in the probability of resolving a greater number of sample components without increasing the analysis time. Comprehensive 2D-GC has proved useful for high-resolution conventional essential oil analysis as well as high-resolution enantioselective essential oil analysis. Combining comprehensive 2D-GC with either a quadrupole or time-of-flight mass spectrometer gives a powerful 3D analysis technique, which is extremely effective for complex sample analysis. The present status and opportunities arising from these ultra-high resolution approaches are discussed herein.",
keywords = "Comprehensive two-dimensional gas chromatography, Enantioselective analysis, Essential oils, GC x GC, High resolution, Mass spectrometry",
author = "Robert Shellie and Philip Marriott",
year = "2003",
month = "5",
day = "1",
doi = "10.1002/ffj.1225",
language = "English",
volume = "18",
pages = "179--191",
journal = "Flavour and Fragrance Journal",
issn = "0882-5734",
publisher = "Wiley-Blackwell",
number = "3",

}

Opportunities for ultra-high resolution analysis of essential oils using comprehensive two-dimensional gas chromatography : A review. / Shellie, Robert; Marriott, Philip.

In: Flavour and Fragrance Journal, Vol. 18, No. 3, 01.05.2003, p. 179-191.

Research output: Contribution to journalReview ArticleResearchpeer-review

TY - JOUR

T1 - Opportunities for ultra-high resolution analysis of essential oils using comprehensive two-dimensional gas chromatography

T2 - A review

AU - Shellie, Robert

AU - Marriott, Philip

PY - 2003/5/1

Y1 - 2003/5/1

N2 - In comprehensive 2D gas chromatography, the entire sample is simultaneously subjected to analysis on two capillary columns. By using a suitable modulation interface between the primary and secondary columns, hundreds of fast, second-dimension chromatograms are produced. The data from these chromatograms are treated such that a 3D surface plot or a 2D contour plot of the components' individual retention times, on each column, as well as peak responses, are represented. In a properly tuned comprehensive 2D chromatogram, the individual sample components are spread throughout a 2D separation space, providing a significant increase in the probability of resolving a greater number of sample components without increasing the analysis time. Comprehensive 2D-GC has proved useful for high-resolution conventional essential oil analysis as well as high-resolution enantioselective essential oil analysis. Combining comprehensive 2D-GC with either a quadrupole or time-of-flight mass spectrometer gives a powerful 3D analysis technique, which is extremely effective for complex sample analysis. The present status and opportunities arising from these ultra-high resolution approaches are discussed herein.

AB - In comprehensive 2D gas chromatography, the entire sample is simultaneously subjected to analysis on two capillary columns. By using a suitable modulation interface between the primary and secondary columns, hundreds of fast, second-dimension chromatograms are produced. The data from these chromatograms are treated such that a 3D surface plot or a 2D contour plot of the components' individual retention times, on each column, as well as peak responses, are represented. In a properly tuned comprehensive 2D chromatogram, the individual sample components are spread throughout a 2D separation space, providing a significant increase in the probability of resolving a greater number of sample components without increasing the analysis time. Comprehensive 2D-GC has proved useful for high-resolution conventional essential oil analysis as well as high-resolution enantioselective essential oil analysis. Combining comprehensive 2D-GC with either a quadrupole or time-of-flight mass spectrometer gives a powerful 3D analysis technique, which is extremely effective for complex sample analysis. The present status and opportunities arising from these ultra-high resolution approaches are discussed herein.

KW - Comprehensive two-dimensional gas chromatography

KW - Enantioselective analysis

KW - Essential oils

KW - GC x GC

KW - High resolution

KW - Mass spectrometry

UR - http://www.scopus.com/inward/record.url?scp=0037613536&partnerID=8YFLogxK

U2 - 10.1002/ffj.1225

DO - 10.1002/ffj.1225

M3 - Review Article

AN - SCOPUS:0037613536

VL - 18

SP - 179

EP - 191

JO - Flavour and Fragrance Journal

JF - Flavour and Fragrance Journal

SN - 0882-5734

IS - 3

ER -