Open tubular-capillary electrochromatography

Developments and applications from 2013 to 2015

Faustino M Tarongoy, Paul R Haddad, Reinhard I Boysen, Milton T W Hearn, Joselito P Quirino

Research output: Contribution to journalReview ArticleResearchpeer-review

Abstract

Open tubular CEC (OT-CEC) separates analyte mixtures by a combination of electrophoretic, electro-osmotic, and/or chromatographic effects. OT-CEC research is an active and growing field, with studies encompassing a wide range of investigations related to new strategies for chemical modification of the inner surface of the capillary, leading to the introduction of novel stationary phase coatings. This review has examined the literature on OT-CEC from 2013 to August 2015 and highlights the developments in the fabrication of highly selective stationary phases, based on materials that include cyclodextrin chiral selectors, graphene and graphene oxide, metal-organic frameworks, molecularly imprinted polymers, nanoparticles, nanolatex particles, nanocomposites, in situ generated polymers, block polymers, tentacle-type polymers, polyelectrolyte multilayers, polysaccharides, phospholipids, and proteins. This review, while considering the development of novel OT-CEC coating materials, specifically examines different immobilization or coating methodologies and approaches and also discusses the separation mechanisms that occur with these new materials. These OT-CEC coatings are intended mainly to separate low molecular weight molecules relevant to the pharmaceutical, agricultural, and food industries as well as for use in environmental monitoring.

Original languageEnglish
Pages (from-to)66-85
Number of pages20
JournalElectrophoresis
Volume37
Issue number1
DOIs
Publication statusPublished - 1 Jan 2016

Keywords

  • Capillary electrochromatography
  • Coating
  • Open-tubular
  • Stationary phase

Cite this

Tarongoy, Faustino M ; Haddad, Paul R ; Boysen, Reinhard I ; Hearn, Milton T W ; Quirino, Joselito P. / Open tubular-capillary electrochromatography : Developments and applications from 2013 to 2015. In: Electrophoresis. 2016 ; Vol. 37, No. 1. pp. 66-85.
@article{b89735199ca541379fc0137e1ceed35d,
title = "Open tubular-capillary electrochromatography: Developments and applications from 2013 to 2015",
abstract = "Open tubular CEC (OT-CEC) separates analyte mixtures by a combination of electrophoretic, electro-osmotic, and/or chromatographic effects. OT-CEC research is an active and growing field, with studies encompassing a wide range of investigations related to new strategies for chemical modification of the inner surface of the capillary, leading to the introduction of novel stationary phase coatings. This review has examined the literature on OT-CEC from 2013 to August 2015 and highlights the developments in the fabrication of highly selective stationary phases, based on materials that include cyclodextrin chiral selectors, graphene and graphene oxide, metal-organic frameworks, molecularly imprinted polymers, nanoparticles, nanolatex particles, nanocomposites, in situ generated polymers, block polymers, tentacle-type polymers, polyelectrolyte multilayers, polysaccharides, phospholipids, and proteins. This review, while considering the development of novel OT-CEC coating materials, specifically examines different immobilization or coating methodologies and approaches and also discusses the separation mechanisms that occur with these new materials. These OT-CEC coatings are intended mainly to separate low molecular weight molecules relevant to the pharmaceutical, agricultural, and food industries as well as for use in environmental monitoring.",
keywords = "Capillary electrochromatography, Coating, Open-tubular, Stationary phase",
author = "Tarongoy, {Faustino M} and Haddad, {Paul R} and Boysen, {Reinhard I} and Hearn, {Milton T W} and Quirino, {Joselito P}",
year = "2016",
month = "1",
day = "1",
doi = "10.1002/elps.201500339",
language = "English",
volume = "37",
pages = "66--85",
journal = "Electrophoresis",
issn = "0173-0835",
publisher = "Wiley-VCH Verlag GmbH & Co. KGaA",
number = "1",

}

Open tubular-capillary electrochromatography : Developments and applications from 2013 to 2015. / Tarongoy, Faustino M; Haddad, Paul R; Boysen, Reinhard I; Hearn, Milton T W; Quirino, Joselito P.

In: Electrophoresis, Vol. 37, No. 1, 01.01.2016, p. 66-85.

Research output: Contribution to journalReview ArticleResearchpeer-review

TY - JOUR

T1 - Open tubular-capillary electrochromatography

T2 - Developments and applications from 2013 to 2015

AU - Tarongoy, Faustino M

AU - Haddad, Paul R

AU - Boysen, Reinhard I

AU - Hearn, Milton T W

AU - Quirino, Joselito P

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Open tubular CEC (OT-CEC) separates analyte mixtures by a combination of electrophoretic, electro-osmotic, and/or chromatographic effects. OT-CEC research is an active and growing field, with studies encompassing a wide range of investigations related to new strategies for chemical modification of the inner surface of the capillary, leading to the introduction of novel stationary phase coatings. This review has examined the literature on OT-CEC from 2013 to August 2015 and highlights the developments in the fabrication of highly selective stationary phases, based on materials that include cyclodextrin chiral selectors, graphene and graphene oxide, metal-organic frameworks, molecularly imprinted polymers, nanoparticles, nanolatex particles, nanocomposites, in situ generated polymers, block polymers, tentacle-type polymers, polyelectrolyte multilayers, polysaccharides, phospholipids, and proteins. This review, while considering the development of novel OT-CEC coating materials, specifically examines different immobilization or coating methodologies and approaches and also discusses the separation mechanisms that occur with these new materials. These OT-CEC coatings are intended mainly to separate low molecular weight molecules relevant to the pharmaceutical, agricultural, and food industries as well as for use in environmental monitoring.

AB - Open tubular CEC (OT-CEC) separates analyte mixtures by a combination of electrophoretic, electro-osmotic, and/or chromatographic effects. OT-CEC research is an active and growing field, with studies encompassing a wide range of investigations related to new strategies for chemical modification of the inner surface of the capillary, leading to the introduction of novel stationary phase coatings. This review has examined the literature on OT-CEC from 2013 to August 2015 and highlights the developments in the fabrication of highly selective stationary phases, based on materials that include cyclodextrin chiral selectors, graphene and graphene oxide, metal-organic frameworks, molecularly imprinted polymers, nanoparticles, nanolatex particles, nanocomposites, in situ generated polymers, block polymers, tentacle-type polymers, polyelectrolyte multilayers, polysaccharides, phospholipids, and proteins. This review, while considering the development of novel OT-CEC coating materials, specifically examines different immobilization or coating methodologies and approaches and also discusses the separation mechanisms that occur with these new materials. These OT-CEC coatings are intended mainly to separate low molecular weight molecules relevant to the pharmaceutical, agricultural, and food industries as well as for use in environmental monitoring.

KW - Capillary electrochromatography

KW - Coating

KW - Open-tubular

KW - Stationary phase

UR - http://www.scopus.com/inward/record.url?scp=84952802844&partnerID=8YFLogxK

UR - http://onlinelibrary.wiley.com/doi/10.1002/elps.201500339/epdf

U2 - 10.1002/elps.201500339

DO - 10.1002/elps.201500339

M3 - Review Article

VL - 37

SP - 66

EP - 85

JO - Electrophoresis

JF - Electrophoresis

SN - 0173-0835

IS - 1

ER -