Abstract
Open tubular CEC (OT-CEC) separates analyte mixtures by a combination of electrophoretic, electro-osmotic, and/or chromatographic effects. OT-CEC research is an active and growing field, with studies encompassing a wide range of investigations related to new strategies for chemical modification of the inner surface of the capillary, leading to the introduction of novel stationary phase coatings. This review has examined the literature on OT-CEC from 2013 to August 2015 and highlights the developments in the fabrication of highly selective stationary phases, based on materials that include cyclodextrin chiral selectors, graphene and graphene oxide, metal-organic frameworks, molecularly imprinted polymers, nanoparticles, nanolatex particles, nanocomposites, in situ generated polymers, block polymers, tentacle-type polymers, polyelectrolyte multilayers, polysaccharides, phospholipids, and proteins. This review, while considering the development of novel OT-CEC coating materials, specifically examines different immobilization or coating methodologies and approaches and also discusses the separation mechanisms that occur with these new materials. These OT-CEC coatings are intended mainly to separate low molecular weight molecules relevant to the pharmaceutical, agricultural, and food industries as well as for use in environmental monitoring.
| Original language | English |
|---|---|
| Pages (from-to) | 66-85 |
| Number of pages | 20 |
| Journal | Electrophoresis |
| Volume | 37 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1 Jan 2016 |
Keywords
- Capillary electrochromatography
- Coating
- Open-tubular
- Stationary phase
Cite this
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Open tubular-capillary electrochromatography : Developments and applications from 2013 to 2015. / Tarongoy, Faustino M; Haddad, Paul R; Boysen, Reinhard I; Hearn, Milton T W; Quirino, Joselito P.
In: Electrophoresis, Vol. 37, No. 1, 01.01.2016, p. 66-85.Research output: Contribution to journal › Review Article › Research › peer-review
TY - JOUR
T1 - Open tubular-capillary electrochromatography
T2 - Developments and applications from 2013 to 2015
AU - Tarongoy, Faustino M
AU - Haddad, Paul R
AU - Boysen, Reinhard I
AU - Hearn, Milton T W
AU - Quirino, Joselito P
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Open tubular CEC (OT-CEC) separates analyte mixtures by a combination of electrophoretic, electro-osmotic, and/or chromatographic effects. OT-CEC research is an active and growing field, with studies encompassing a wide range of investigations related to new strategies for chemical modification of the inner surface of the capillary, leading to the introduction of novel stationary phase coatings. This review has examined the literature on OT-CEC from 2013 to August 2015 and highlights the developments in the fabrication of highly selective stationary phases, based on materials that include cyclodextrin chiral selectors, graphene and graphene oxide, metal-organic frameworks, molecularly imprinted polymers, nanoparticles, nanolatex particles, nanocomposites, in situ generated polymers, block polymers, tentacle-type polymers, polyelectrolyte multilayers, polysaccharides, phospholipids, and proteins. This review, while considering the development of novel OT-CEC coating materials, specifically examines different immobilization or coating methodologies and approaches and also discusses the separation mechanisms that occur with these new materials. These OT-CEC coatings are intended mainly to separate low molecular weight molecules relevant to the pharmaceutical, agricultural, and food industries as well as for use in environmental monitoring.
AB - Open tubular CEC (OT-CEC) separates analyte mixtures by a combination of electrophoretic, electro-osmotic, and/or chromatographic effects. OT-CEC research is an active and growing field, with studies encompassing a wide range of investigations related to new strategies for chemical modification of the inner surface of the capillary, leading to the introduction of novel stationary phase coatings. This review has examined the literature on OT-CEC from 2013 to August 2015 and highlights the developments in the fabrication of highly selective stationary phases, based on materials that include cyclodextrin chiral selectors, graphene and graphene oxide, metal-organic frameworks, molecularly imprinted polymers, nanoparticles, nanolatex particles, nanocomposites, in situ generated polymers, block polymers, tentacle-type polymers, polyelectrolyte multilayers, polysaccharides, phospholipids, and proteins. This review, while considering the development of novel OT-CEC coating materials, specifically examines different immobilization or coating methodologies and approaches and also discusses the separation mechanisms that occur with these new materials. These OT-CEC coatings are intended mainly to separate low molecular weight molecules relevant to the pharmaceutical, agricultural, and food industries as well as for use in environmental monitoring.
KW - Capillary electrochromatography
KW - Coating
KW - Open-tubular
KW - Stationary phase
UR - http://www.scopus.com/inward/record.url?scp=84952802844&partnerID=8YFLogxK
UR - http://onlinelibrary.wiley.com/doi/10.1002/elps.201500339/epdf
U2 - 10.1002/elps.201500339
DO - 10.1002/elps.201500339
M3 - Review Article
VL - 37
SP - 66
EP - 85
JO - Electrophoresis
JF - Electrophoresis
SN - 0173-0835
IS - 1
ER -