One-pot synthesis of benzo[b]furan and indole inhibitors of tubulin polymerization

Bernard L. Flynn, Ernest Hamel, M. Katherine Jung

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253 Citations (Scopus)

Abstract

Benzo[b]furan and indole analogues of some recently identified benzo[b]thiophene inhibitors of tubulin polymerization have been prepared, and their biological activity has been assessed. Several very potent analogues were identified.

Original languageEnglish
Pages (from-to)2670-2673
Number of pages4
JournalJournal of Medicinal Chemistry
Volume45
Issue number12
DOIs
Publication statusPublished - 6 Jun 2002
Externally publishedYes

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