TY - JOUR
T1 - One-pot selective homodimerization/hydrogenation strategy for sequential dicarba bridge formation
AU - Burnley, James
AU - Jackson, William Roy
AU - Robinson, Andrea Jane
PY - 2015
Y1 - 2015
N2 - The installation of interlocked dicarba bridges into peptide sequences requires the development of a regioselective and chemoselective methodology. This manuscript describes a one-pot, chemoselective synthesis of three 2,7-diaminosuberic acid derivatives from an alkyne, a cobalt-carbonyl protected alkyne, and an alkene using metathesis and homogeneous hydrogenation catalysis
AB - The installation of interlocked dicarba bridges into peptide sequences requires the development of a regioselective and chemoselective methodology. This manuscript describes a one-pot, chemoselective synthesis of three 2,7-diaminosuberic acid derivatives from an alkyne, a cobalt-carbonyl protected alkyne, and an alkene using metathesis and homogeneous hydrogenation catalysis
U2 - 10.1021/acs.joc.5b01312
DO - 10.1021/acs.joc.5b01312
M3 - Article
VL - 80
SP - 9057
EP - 9063
JO - The Journal of Organic Chemistry
JF - The Journal of Organic Chemistry
SN - 0022-3263
IS - 18
ER -