On the trail of empty MHC class-I

Alexander Theodossis

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)


Since being proposed nearly 25years ago that MHC-I molecules free of peptide ligand possess a conformation that is distinct from that of the mature loaded form, considerable research has been conducted in order to isolate and characterise such a species. While some progress has been made in our understanding, many questions still surround the nature and loading of empty MHC-I. However, the necessary tools to address these questions may finally be at hand.
Original languageEnglish
Pages (from-to)131 - 134
Number of pages4
JournalMolecular Immunology
Issue number2
Publication statusPublished - 2013

Cite this