On-demand picoliter-scale droplet generation using surface acoustic waves

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearch

Abstract

Droplets are a versatile platform for performing chemical reactions, detection and compartmentalization. When a droplet is in a two-phase device droplet-based processes can be performed without the need for fluid handling, with small reaction volumes reducing the need to perform separate mixing steps and reducing reaction times. While techniques exist to produce continuous trains of water-in-oil droplets, it has been difficult to produce individual droplets on-demand, a prerequisite for more complex programmable microfluidic devices. Here we present a novel method for integrating a pressure source on-chip, producing picoliter scale water-in-oil droplets on-demand using surface acoustic waves.

Original languageEnglish
Title of host publication17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, (MicroTAS 2013)
Subtitle of host publicationFreiburg, Germany; 27-31 October 2013
PublisherChemical and Biological Microsystems Society
Pages1604-1606
Number of pages3
Volume3
ISBN (Print)9781632666246
Publication statusPublished - 2013
EventInternational Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013) - Freiburg, Germany
Duration: 27 Oct 201331 Oct 2013
Conference number: 17th

Conference

ConferenceInternational Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013)
Abbreviated titleMicroTAS 2013
CountryGermany
CityFreiburg
Period27/10/1331/10/13

Keywords

  • Acoustic
  • Droplet
  • Microfluidics
  • Surface acoustic waves

Cite this

Collins, D. J., Alan, T., Helmerson, K., & Neild, A. (2013). On-demand picoliter-scale droplet generation using surface acoustic waves. In 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, (MicroTAS 2013): Freiburg, Germany; 27-31 October 2013 (Vol. 3, pp. 1604-1606). Chemical and Biological Microsystems Society.
Collins, D.J. ; Alan, Tuncay ; Helmerson, Kristian ; Neild, Adrian. / On-demand picoliter-scale droplet generation using surface acoustic waves. 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, (MicroTAS 2013): Freiburg, Germany; 27-31 October 2013. Vol. 3 Chemical and Biological Microsystems Society, 2013. pp. 1604-1606
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Collins, DJ, Alan, T, Helmerson, K & Neild, A 2013, On-demand picoliter-scale droplet generation using surface acoustic waves. in 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, (MicroTAS 2013): Freiburg, Germany; 27-31 October 2013. vol. 3, Chemical and Biological Microsystems Society, pp. 1604-1606, International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013), Freiburg, Germany, 27/10/13.

On-demand picoliter-scale droplet generation using surface acoustic waves. / Collins, D.J.; Alan, Tuncay; Helmerson, Kristian; Neild, Adrian.

17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, (MicroTAS 2013): Freiburg, Germany; 27-31 October 2013. Vol. 3 Chemical and Biological Microsystems Society, 2013. p. 1604-1606.

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearch

TY - GEN

T1 - On-demand picoliter-scale droplet generation using surface acoustic waves

AU - Collins, D.J.

AU - Alan, Tuncay

AU - Helmerson, Kristian

AU - Neild, Adrian

PY - 2013

Y1 - 2013

N2 - Droplets are a versatile platform for performing chemical reactions, detection and compartmentalization. When a droplet is in a two-phase device droplet-based processes can be performed without the need for fluid handling, with small reaction volumes reducing the need to perform separate mixing steps and reducing reaction times. While techniques exist to produce continuous trains of water-in-oil droplets, it has been difficult to produce individual droplets on-demand, a prerequisite for more complex programmable microfluidic devices. Here we present a novel method for integrating a pressure source on-chip, producing picoliter scale water-in-oil droplets on-demand using surface acoustic waves.

AB - Droplets are a versatile platform for performing chemical reactions, detection and compartmentalization. When a droplet is in a two-phase device droplet-based processes can be performed without the need for fluid handling, with small reaction volumes reducing the need to perform separate mixing steps and reducing reaction times. While techniques exist to produce continuous trains of water-in-oil droplets, it has been difficult to produce individual droplets on-demand, a prerequisite for more complex programmable microfluidic devices. Here we present a novel method for integrating a pressure source on-chip, producing picoliter scale water-in-oil droplets on-demand using surface acoustic waves.

KW - Acoustic

KW - Droplet

KW - Microfluidics

KW - Surface acoustic waves

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SN - 9781632666246

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BT - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, (MicroTAS 2013)

PB - Chemical and Biological Microsystems Society

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Collins DJ, Alan T, Helmerson K, Neild A. On-demand picoliter-scale droplet generation using surface acoustic waves. In 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, (MicroTAS 2013): Freiburg, Germany; 27-31 October 2013. Vol. 3. Chemical and Biological Microsystems Society. 2013. p. 1604-1606