OMERACT 2023 Systemic Lupus Erythematosus Special Interest Group: Winnowing and Binning Preliminary Candidate Domains for the Core Outcome Set

Wils Nielsen, Vibeke Strand, Lee S. Simon, Ioannis Parodis, Alfred H.J. Kim, Maya Desai, Yvonne Enman, Daniel Wallace, Yashaar Chaichian, Sandra Navarra, Cynthia Aranow, Meggan MacKay, Kimberly Trotter, Oshrat E. Tayer-Shifman, Ali Duarte-Garcia, Lai Shan Tam, Manuel F. Ugarte-Gil, Guillermo J. PonsEstel, John A. Reynolds, Mandana NikpourAlberta Hoi, Juanita Romero-Diaz, Danaë Papachristos, Amita Aggarwal, Chi Chiu Mok, Keishi Fujio, Rosalind Ramsey-Goldman, Aaron Howe, Behdin Nowrouzi Kia, Dennisse Bonilla, Julian Thumboo, Marta Mosca, Martin Aringer, Sindhu R. Johnson, Aaron M. Drucker, Eric Morand, Ian Bruce, Zahi Touma, on behalf of the OMERACT SLE Working Group

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Abstract

Background: The Outcome Measures in Rheumatology (OMERACT) Systemic Lupus Erythematosus (SLE) Working Group held a Special Interest Group (SIG) at the OMERACT 2023 conference in Colorado Springs where SLE collaborators reviewed domain sub-themes generated through qualitative research and literature review. Objective: The objective of the SIG and the subsequent meetings of the SLE Working Group was to begin the winnowing and binning of candidate domain sub-themes into a preliminary list of candidate domains that will proceed to the consensus Delphi exercise for the SLE COS. Methods: Four breakout groups at the SLE SIG in Colorado Springs winnowed and binned 132 domain sub-themes into candidate domains, which was continued with a series of virtual meetings by an advisory group of SLE patient research partners (PRPs), members of the OMERACT SLE Working Group Steering Committee, and other collaborators. Results: The 132 domain sub-themes were reduced to a preliminary list of 20 candidate domains based on their clinical and research relevance for clinical trials and research studies. Conclusion: A meaningful and substantial winnowing and binning of candidate domains for the SLE COS was achieved resulting in a preliminary list of 20 candidate domains.

Original languageEnglish
Article number152380
Number of pages6
JournalSeminars in Arthritis and Rheumatism
Volume65
DOIs
Publication statusPublished - Apr 2024

Keywords

  • Core Outcome Set
  • OMERACT
  • Systemic Lupus Erythematosus

Cite this