Older first-time mothers and early postpartum depression: A prospective cohort study of women conceiving spontaneously or with assisted reproductive technologies

C A McMahon, Jacky Boivin, F L Gibson, Jane Fisher, Karin Hammarberg, Karen Wynter, Doug Saunders

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Abstract

Objective: To evaluate whether older first-time mothers (≥37 years) have higher rates of postpartum depression compared with younger first-time mothers, controlling for mode of conception and known risk factors for postpartum depression.

Design: Prospective cohort study.

Setting: Assisted reproductive technology (ART) clinics in two large Australian cities and public and private antenatal clinics and/or classes in the vicinity of ART clinics.

Patient(s): Nulliparous women who had conceived spontaneously (n = 295) or through ART (n = 297) in three age-groups: younger, 20 to 30 years (n = 173); middle, 31 to 36 years (n = 214); and older, ≥37 years (n = 189).

Intervention(s): Semistructured interviews and questionnaires.

Main Outcome Measure(s): Major depressive disorder in the first 4 months after birth as assessed by structured diagnostic interview.

Result(s): The study performed 592 complete pregnancy assessments and 541 postpartum assessments. The prevalence of major depressive disorder was 7.9%, at the lower end of community rates. Neither maternal age-group nor mode of conception was statistically significantly related to depression.

Conclusion(s): Older first-time mothers, whether conceiving through ART or spontaneously, do not show increased vulnerability to postnatal depression.
Original languageEnglish
Pages (from-to)1218 - 1224
Number of pages7
JournalFertility and Sterility
Volume96
Issue number5
DOIs
Publication statusPublished - 2011

Cite this

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title = "Older first-time mothers and early postpartum depression: A prospective cohort study of women conceiving spontaneously or with assisted reproductive technologies",
abstract = "Objective: To evaluate whether older first-time mothers (≥37 years) have higher rates of postpartum depression compared with younger first-time mothers, controlling for mode of conception and known risk factors for postpartum depression.Design: Prospective cohort study.Setting: Assisted reproductive technology (ART) clinics in two large Australian cities and public and private antenatal clinics and/or classes in the vicinity of ART clinics.Patient(s): Nulliparous women who had conceived spontaneously (n = 295) or through ART (n = 297) in three age-groups: younger, 20 to 30 years (n = 173); middle, 31 to 36 years (n = 214); and older, ≥37 years (n = 189).Intervention(s): Semistructured interviews and questionnaires.Main Outcome Measure(s): Major depressive disorder in the first 4 months after birth as assessed by structured diagnostic interview.Result(s): The study performed 592 complete pregnancy assessments and 541 postpartum assessments. The prevalence of major depressive disorder was 7.9{\%}, at the lower end of community rates. Neither maternal age-group nor mode of conception was statistically significantly related to depression.Conclusion(s): Older first-time mothers, whether conceiving through ART or spontaneously, do not show increased vulnerability to postnatal depression.",
author = "McMahon, {C A} and Jacky Boivin and Gibson, {F L} and Jane Fisher and Karin Hammarberg and Karen Wynter and Doug Saunders",
year = "2011",
doi = "10.1016/j.fertnstert.2011.08.037",
language = "English",
volume = "96",
pages = "1218 -- 1224",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier",
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Older first-time mothers and early postpartum depression : A prospective cohort study of women conceiving spontaneously or with assisted reproductive technologies. / McMahon, C A; Boivin, Jacky; Gibson, F L; Fisher, Jane; Hammarberg, Karin; Wynter, Karen; Saunders, Doug.

In: Fertility and Sterility, Vol. 96, No. 5, 2011, p. 1218 - 1224.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Older first-time mothers and early postpartum depression

T2 - A prospective cohort study of women conceiving spontaneously or with assisted reproductive technologies

AU - McMahon, C A

AU - Boivin, Jacky

AU - Gibson, F L

AU - Fisher, Jane

AU - Hammarberg, Karin

AU - Wynter, Karen

AU - Saunders, Doug

PY - 2011

Y1 - 2011

N2 - Objective: To evaluate whether older first-time mothers (≥37 years) have higher rates of postpartum depression compared with younger first-time mothers, controlling for mode of conception and known risk factors for postpartum depression.Design: Prospective cohort study.Setting: Assisted reproductive technology (ART) clinics in two large Australian cities and public and private antenatal clinics and/or classes in the vicinity of ART clinics.Patient(s): Nulliparous women who had conceived spontaneously (n = 295) or through ART (n = 297) in three age-groups: younger, 20 to 30 years (n = 173); middle, 31 to 36 years (n = 214); and older, ≥37 years (n = 189).Intervention(s): Semistructured interviews and questionnaires.Main Outcome Measure(s): Major depressive disorder in the first 4 months after birth as assessed by structured diagnostic interview.Result(s): The study performed 592 complete pregnancy assessments and 541 postpartum assessments. The prevalence of major depressive disorder was 7.9%, at the lower end of community rates. Neither maternal age-group nor mode of conception was statistically significantly related to depression.Conclusion(s): Older first-time mothers, whether conceiving through ART or spontaneously, do not show increased vulnerability to postnatal depression.

AB - Objective: To evaluate whether older first-time mothers (≥37 years) have higher rates of postpartum depression compared with younger first-time mothers, controlling for mode of conception and known risk factors for postpartum depression.Design: Prospective cohort study.Setting: Assisted reproductive technology (ART) clinics in two large Australian cities and public and private antenatal clinics and/or classes in the vicinity of ART clinics.Patient(s): Nulliparous women who had conceived spontaneously (n = 295) or through ART (n = 297) in three age-groups: younger, 20 to 30 years (n = 173); middle, 31 to 36 years (n = 214); and older, ≥37 years (n = 189).Intervention(s): Semistructured interviews and questionnaires.Main Outcome Measure(s): Major depressive disorder in the first 4 months after birth as assessed by structured diagnostic interview.Result(s): The study performed 592 complete pregnancy assessments and 541 postpartum assessments. The prevalence of major depressive disorder was 7.9%, at the lower end of community rates. Neither maternal age-group nor mode of conception was statistically significantly related to depression.Conclusion(s): Older first-time mothers, whether conceiving through ART or spontaneously, do not show increased vulnerability to postnatal depression.

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