TY - JOUR
T1 - Off-label prescribing in the midst of a pandemic
T2 - The case of hydroxychloroquine
AU - Bell, J. Simon
AU - Bell, John A.
AU - Creek, Darren J.
PY - 2020/4/8
Y1 - 2020/4/8
N2 - In the middle ages, the deadly, feverish illness endemic throughout most of the world was known as ague. The term ‘mal’aria’ was unknown in English until the 18th century, but the alleged cure, derived from the South American cinchona tree, had already been in use for 100 years.1 In the treatment of malaria, quinine (the active ingredient in cinchona bark) and its chemical successors chloroquine and hydroxychloroquine have largely been superseded by more effective, less toxic medications; hydroxychloroquine is reserved for still significant but less common conditions.
AB - In the middle ages, the deadly, feverish illness endemic throughout most of the world was known as ague. The term ‘mal’aria’ was unknown in English until the 18th century, but the alleged cure, derived from the South American cinchona tree, had already been in use for 100 years.1 In the treatment of malaria, quinine (the active ingredient in cinchona bark) and its chemical successors chloroquine and hydroxychloroquine have largely been superseded by more effective, less toxic medications; hydroxychloroquine is reserved for still significant but less common conditions.
UR - http://www.scopus.com/inward/record.url?scp=85083419319&partnerID=8YFLogxK
U2 - 10.31128/AJGP-COVID-06
DO - 10.31128/AJGP-COVID-06
M3 - Article
C2 - 32279469
AN - SCOPUS:85083419319
JO - Australian Journal of General Practice
JF - Australian Journal of General Practice
SN - 2208-794X
ER -