Obesity, arthritis, and gout

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Osteoarthritis (OA) is the most prevalent chronic joint disease, characterized by pain and loss of function attributable to changes affecting the whole joint, including articular cartilage and subchondral bone, which result in radiological changes. The knee, hip, and hand joints are most commonly affected. Treatments for OA are largely symptomatic, including paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs) for pain relief and total joint replacement for the treatment of end-stage symptomatic OA. Therapy aimed at reducing disease progression is limited.

Original languageEnglish
Title of host publicationHandbook of Obesity
Subtitle of host publicationEpidemiology, Etiology and Physiopathology
EditorsGeorge A. Bray, Claude Bouchard
Place of PublicationBoca Raton FL USA
PublisherCRC Press
Number of pages9
ISBN (Electronic)9781842145579
ISBN (Print)9781842145562
Publication statusPublished - 1 Jan 2014

Cite this

Dawson, L., Wluka, A. E., Wang, Y., & Cicuttini, F. M. (2014). Obesity, arthritis, and gout. In G. A. Bray, & C. Bouchard (Eds.), Handbook of Obesity: Epidemiology, Etiology and Physiopathology (3rd ed., Vol. 1, pp. 625-633). CRC Press.