OARSI Clinical Trials Recommendations: Hip imaging in clinical trials in osteoarthritis

G. E. Gold, F. Cicuttini, M. D. Crema, F. Eckstein, A. Guermazi, R. Kijowski, T. M. Link, E. Maheu, J. Martel-Pelletier, C. G. Miller, J. P. Pelletier, C. G. Peterfy, H. G. Potter, F. W. Roemer, D. J. Hunter

Research output: Contribution to journalReview ArticleResearchpeer-review

27 Citations (Scopus)

Abstract

Imaging of hip in osteoarthritis (OA) has seen considerable progress in the past decade, with the introduction of new techniques that may be more sensitive to structural disease changes. The purpose of this expert opinion, consensus driven recommendation is to provide detail on how to apply hip imaging in disease modifying clinical trials. It includes information on acquisition methods/techniques (including guidance on positioning for radiography, sequence/protocol recommendations/hardware for magnetic resonance imaging (MRI)); commonly encountered problems (including positioning, hardware and coil failures, artifacts associated with various MRI sequences); quality assurance/control procedures; measurement methods; measurement performance (reliability, responsiveness, and validity); recommendations for trials; and research recommendations.

Original languageEnglish
Pages (from-to)716-731
Number of pages16
JournalOsteoarthritis and Cartilage
Volume23
Issue number5
DOIs
Publication statusPublished - May 2015

Keywords

  • Clinical trial guidelines
  • Hip osteoarthritis
  • Imaging

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