TY - JOUR
T1 - Nutrition and functional outcomes after critical illness due to pandemic (H1N1) 2009 influenza
T2 - A retrospective cohort study
AU - Bedford, James R.
AU - Ivermee, Clare L.
AU - Lange, Kylie
AU - Chapman, Marianne J.
PY - 2011
Y1 - 2011
N2 - Objective: To determine functional outcomes 6 months after intensive care unit admission for severe infection due to pandemic (H1N1) 2009 influenza and examine the relationship between nutrition during ICU admission and outcome. Design, setting and participants: Retrospective cohort study of patients with confirmed H1N1 influenza admitted to the ICU, Royal Adelaide Hospital, South Australia, June- October 2009. Main outcome measures: Data were collected from medical records, dietitian notes and the daily ICU chart and included: demographics, daily kilocalories (Kcal) and protein delivered compared with dietitian-calculated requirement, ICU and hospital length of stay. Weight change and functional outcome at 6 months were determined prospectively by telephone interview using the 12-Item Short Form Health Survey and the EuroQol Group 5-Dimension Questionnaire. Results: Of 25 patients with H1N1 infection, 23 were included in the study (14 men; median age, 48 years (interquartile range [IQR], 39-55 years); median Acute Physiology and Chronic Health Evaluation (APACHE) II score, 17 (IQR, 13-21); median ICU length of stay, 9 days (IQR, 4-15 days); median hospital length of stay, 20 days (IQR, 11-30 days); ICU mortality, 3 (13%; 95% CI, 4%- 33%). Enteral feeding was commenced in 16 patients, who received a mean of 71% (SD, 27%; 95% CI, 57%-86%) of their energy and 62% (SD, 25%; 95% CI, 49%-75%) of their protein goals over their ICU stay. A more negative protein balance was associated with prolonged ICU stay (r =-0.746; P = 0.003). Reduced success of feeding was associated with increased severity of illness and shorter ICU length of stay. Patients reported a good functional outcome at 6 months. Conclusions: Patients admitted to this ICU with H1N1 infection were fed successfully during their stay. Critically ill patients surviving H1N1 infection had good functional outcomes at 6 months.
AB - Objective: To determine functional outcomes 6 months after intensive care unit admission for severe infection due to pandemic (H1N1) 2009 influenza and examine the relationship between nutrition during ICU admission and outcome. Design, setting and participants: Retrospective cohort study of patients with confirmed H1N1 influenza admitted to the ICU, Royal Adelaide Hospital, South Australia, June- October 2009. Main outcome measures: Data were collected from medical records, dietitian notes and the daily ICU chart and included: demographics, daily kilocalories (Kcal) and protein delivered compared with dietitian-calculated requirement, ICU and hospital length of stay. Weight change and functional outcome at 6 months were determined prospectively by telephone interview using the 12-Item Short Form Health Survey and the EuroQol Group 5-Dimension Questionnaire. Results: Of 25 patients with H1N1 infection, 23 were included in the study (14 men; median age, 48 years (interquartile range [IQR], 39-55 years); median Acute Physiology and Chronic Health Evaluation (APACHE) II score, 17 (IQR, 13-21); median ICU length of stay, 9 days (IQR, 4-15 days); median hospital length of stay, 20 days (IQR, 11-30 days); ICU mortality, 3 (13%; 95% CI, 4%- 33%). Enteral feeding was commenced in 16 patients, who received a mean of 71% (SD, 27%; 95% CI, 57%-86%) of their energy and 62% (SD, 25%; 95% CI, 49%-75%) of their protein goals over their ICU stay. A more negative protein balance was associated with prolonged ICU stay (r =-0.746; P = 0.003). Reduced success of feeding was associated with increased severity of illness and shorter ICU length of stay. Patients reported a good functional outcome at 6 months. Conclusions: Patients admitted to this ICU with H1N1 infection were fed successfully during their stay. Critically ill patients surviving H1N1 infection had good functional outcomes at 6 months.
UR - http://www.scopus.com/inward/record.url?scp=84857091288&partnerID=8YFLogxK
M3 - Article
C2 - 22129283
AN - SCOPUS:84857091288
SN - 1441-2772
VL - 13
SP - 226
EP - 231
JO - Critical Care and Resuscitation
JF - Critical Care and Resuscitation
IS - 4
ER -