Nuclear receptor expression in human differentiated thyroid tumors

Michael Mond; Maria Alexiadis; Natalie Eriksson; Melissa J Davis; George E O Muscat; Peter J Fuller; Christopher P Gilfillan

doi:10.1089/thy.2013.0509

Nuclear receptor expression in human differentiated thyroid tumors

Michael Mond, Maria Alexiadis, Natalie Eriksson, Melissa J Davis, George E O Muscat, Peter J Fuller, Christopher P Gilfillan

Eastern Health Clinical School

Research output: Contribution to journal › Article › Research › peer-review

13 Citations (Scopus)

Abstract

Background: Nuclear receptors (NRs) play a key role in endocrine signaling and metabolism and are important therapeutic targets in a number of hormone-dependent malignancies. Studies on the role of NRs in thyroid cancer are limited. Objective: The objective of the study was to examine systematically the expression of the 48 human NRs in a series of benign and malignant thyroid tissues. Within the papillary carcinoma cohort, we sought to determine if NR expression differed significantly by BRAF mutation status.

Original language	English
Pages (from-to)	1000 - 1011
Number of pages	12
Journal	Thyroid
Volume	24
Issue number	6
DOIs	https://doi.org/10.1089/thy.2013.0509
Publication status	Published - 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1089/thy.2013.0509

Cite this

@article{2f5cc992be75442eab53c244e2d08ab5,

title = "Nuclear receptor expression in human differentiated thyroid tumors",

abstract = "Background: Nuclear receptors (NRs) play a key role in endocrine signaling and metabolism and are important therapeutic targets in a number of hormone-dependent malignancies. Studies on the role of NRs in thyroid cancer are limited. Objective: The objective of the study was to examine systematically the expression of the 48 human NRs in a series of benign and malignant thyroid tissues. Within the papillary carcinoma cohort, we sought to determine if NR expression differed significantly by BRAF mutation status.",

author = "Michael Mond and Maria Alexiadis and Natalie Eriksson and Davis, {Melissa J} and Muscat, {George E O} and Fuller, {Peter J} and Gilfillan, {Christopher P}",

year = "2014",

doi = "10.1089/thy.2013.0509",

language = "English",

volume = "24",

pages = "1000 -- 1011",

journal = "Thyroid",

issn = "1050-7256",

publisher = "Mary Ann Liebert Inc",

number = "6",

}

TY - JOUR

T1 - Nuclear receptor expression in human differentiated thyroid tumors

AU - Mond, Michael

AU - Alexiadis, Maria

AU - Eriksson, Natalie

AU - Davis, Melissa J

AU - Muscat, George E O

AU - Fuller, Peter J

AU - Gilfillan, Christopher P

PY - 2014

Y1 - 2014

N2 - Background: Nuclear receptors (NRs) play a key role in endocrine signaling and metabolism and are important therapeutic targets in a number of hormone-dependent malignancies. Studies on the role of NRs in thyroid cancer are limited. Objective: The objective of the study was to examine systematically the expression of the 48 human NRs in a series of benign and malignant thyroid tissues. Within the papillary carcinoma cohort, we sought to determine if NR expression differed significantly by BRAF mutation status.

AB - Background: Nuclear receptors (NRs) play a key role in endocrine signaling and metabolism and are important therapeutic targets in a number of hormone-dependent malignancies. Studies on the role of NRs in thyroid cancer are limited. Objective: The objective of the study was to examine systematically the expression of the 48 human NRs in a series of benign and malignant thyroid tissues. Within the papillary carcinoma cohort, we sought to determine if NR expression differed significantly by BRAF mutation status.

UR - http://online.liebertpub.com/doi/pdf/10.1089/thy.2013.0509

U2 - 10.1089/thy.2013.0509

DO - 10.1089/thy.2013.0509

M3 - Article

VL - 24

SP - 1000

EP - 1011

JO - Thyroid

JF - Thyroid

SN - 1050-7256

IS - 6

ER -

Nuclear receptor expression in human differentiated thyroid tumors

Abstract

UN SDGs

Access to Document

Other files and links

Cite this