Abstract
Background: Nuclear receptors (NRs) play a key role in endocrine signaling and metabolism and are important therapeutic targets in a number of hormone-dependent malignancies. Studies on the role of NRs in thyroid cancer are limited. Objective: The objective of the study was to examine systematically the expression of the 48 human NRs in a series of benign and malignant thyroid tissues. Within the papillary carcinoma cohort, we sought to determine if NR expression differed significantly by BRAF mutation status.
Original language | English |
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Pages (from-to) | 1000 - 1011 |
Number of pages | 12 |
Journal | Thyroid |
Volume | 24 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2014 |