N6-(5,6-epoxynorbornyl)adenosine analogs as A1adenosine agonists

Denis M.J. Wright, Stephen P. Baker, Scott G. Stewart, Peter J. Scammells

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)


A range of related adenosines and 5'-N-ethylcarboxamidoadenosines bearing oxygenated substituents in the N6position have been synthesised and evaluated as A1-adenosine receptor ligands. Compound 9 emerged with potent affinity (EC50= 1.1 nM).
Original languageEnglish
Pages (from-to)3647-3648
Number of pages2
JournalBioorganic and Medicinal Chemistry Letters
Issue number24
Publication statusPublished - 15 Dec 1998

Cite this