TY - JOUR
T1 - Novel use of prasugrel for intracranial stent thrombosis
AU - Leslie-Mazwi, Thabele M
AU - Chandra, Ronil V.
AU - Oh, Daniel C.
AU - Nogueira, Raul Gomes
PY - 2011/12
Y1 - 2011/12
N2 - Dual antiplatelet therapy is established for prevention of stent thrombosis in cardiac patients, and widely utilized in neurointerventional stent cases. Aspirin and clopidogrel are typically synergistic. We present a case of clopidogrel resistance due to genetic polymorphism resulting in acute stent thrombosis during elective stent-assisted coiling, with novel use of prasugrel as an alternative platelet inhibitor in the neurovascular setting.
AB - Dual antiplatelet therapy is established for prevention of stent thrombosis in cardiac patients, and widely utilized in neurointerventional stent cases. Aspirin and clopidogrel are typically synergistic. We present a case of clopidogrel resistance due to genetic polymorphism resulting in acute stent thrombosis during elective stent-assisted coiling, with novel use of prasugrel as an alternative platelet inhibitor in the neurovascular setting.
UR - http://www.scopus.com/inward/record.url?scp=81155137238&partnerID=8YFLogxK
U2 - 10.1136/jnis.2010.004382
DO - 10.1136/jnis.2010.004382
M3 - Article
AN - SCOPUS:81155137238
SN - 1759-8478
VL - 3
SP - 358
EP - 360
JO - Journal of NeuroInterventional Surgery
JF - Journal of NeuroInterventional Surgery
IS - 4
ER -