Novel pathway for sudden cardiac death prevention

Eyal Herzog, Emad F. Aziz, Marrick Kukin, Jonathan S. Steinberg, Suneet Mittal

Research output: Contribution to journalReview ArticleResearchpeer-review

2 Citations (Scopus)


Sudden cardiac death is one of the leading causes of death in the United States, accounting for an estimate 350,000 deaths each year. The US Congress passed a resolution in late September 2008 designating October as "National Sudden Cardiac Arrest Awareness Month." In an effort to raise awareness for preventing unnecessary deaths because of sudden cardiac death, the resolution "calls upon the people of the United States to observe this month with appropriate programs and activities." The response from our institute was to develop a novel pathway named ESCAPE-which is an evidence-based novel pathway for low Ejection fraction and Sudden Cardiac death Awareness and Prevention Eligibility. The main objective of this program is to demonstrate that implementing a simple novel pathway for primary prevention of sudden cardiac arrest leads to an increase in the number of patients with low ejection fraction (≤35%) referred for implantable cardioverter defibrillators therapy. The key difference of our pathway compared with prior reported algorithms is that it is initiated at imaging laboratories. The registry will consist of consecutive patients presenting to our imaging laboratories (the echocardiography, the nuclear, and the cardiac catheterization laboratories). The ESCAPE pathway defines patients' management based upon 3 key parameters: left ventricular ejection function, heart failure functional class, and an evidence of a prior myocardial infarction or coronary artery disease. We hope that this new novel pathway will help to bridge the gap between the complex guidelines and the actual clinical practice and will help to save many lives.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalCritical Pathways in Cardiology
Issue number1
Publication statusPublished - Mar 2009
Externally publishedYes


  • Clinical pathway
  • Heart failure
  • ICD
  • Sudden cardiac death

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