Novel antithrombotic drugs on the Horizon: The ultimate promise to prevent clotting while avoiding bleeding

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9 Citations (Scopus)

Abstract

Diseases associated with arterial thrombosis or venous thrombosis are leading causes of mortality and morbidity globally. Since the 1930s, antithrombotic therapy has been the cornerstone of medical therapy for thrombotic diseases. However, the success of antithrombotic therapy has come at the cost of one of the most dreaded iatrogenic complications - bleeding. Recently, new evidence has emerged on potentially important differences between thrombosis and hemostasis, thereby raising the possibility of developing new antithrombotic drugs that do not cause bleeding.

Original languageEnglish
Pages (from-to)1133-1135
Number of pages3
JournalCirculation Research
Volume121
Issue number10
DOIs
Publication statusPublished - 1 Jan 2017

Keywords

  • Acute coronary syndromes
  • Anticoagulants
  • Aspirin
  • Fibrin
  • Hemorrhage
  • Platelets
  • Thrombosis

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