Novel agrochemical conjugates with self-assembling behaviour

Qingtao Liu, Bim Graham, Adrian Hawley, Yao Da Dong, Ben J. Boyd

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Hypothesis: That conjugation of agrichemicals to pro-assembly hydrophobic moieties will enable enhanced compatibility and loading with host lyotropic liquid crystalline carrier matrix, and potentially self-assemble in their own right in aqueous environments. Experiments: A series of lipid-like agrochemical-conjugates were synthesized using specific amphiphilic entities conjugated onto the agrochemicals, picloram and 2,4-dichlorophenoxyacetic acid (2,4-D). The self-assembly behaviour and compatibility of the novel entities when incorporated into phytantriol and monoolein-based liquid crystalline systems were examined using small angle X-ray scattering, cryo-TEM and polarized optical microscopy. Findings: Compared to agrochemical-conjugates with simple alkyl ester groups, the esterification of the agrochemicals with amphiphilic groups such as phytantriol and monoolein led to greater structural compatibility and consequently a greater loading of the agrochemicals in the liquid crystalline systems without destabilizing phase structure. Picloram-monoolein and picloram-monoelaidin can self-assemble to form lamellar structures in water. However, certain agrochemical-conjugates such as picloram-monoelaidin and picloram-PEGn-oleate showed poor compatibility with liquid crystalline systems, resulting in phase separation.

Original languageEnglish
Pages (from-to)369-378
Number of pages10
JournalJournal of Colloid and Interface Science
Volume512
DOIs
Publication statusPublished - 15 Feb 2018

Keywords

  • Agricultural chemical
  • Lyotropic liquid crystal
  • Self assembly

Cite this

Liu, Qingtao ; Graham, Bim ; Hawley, Adrian ; Dong, Yao Da ; Boyd, Ben J. / Novel agrochemical conjugates with self-assembling behaviour. In: Journal of Colloid and Interface Science. 2018 ; Vol. 512. pp. 369-378.
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Novel agrochemical conjugates with self-assembling behaviour. / Liu, Qingtao; Graham, Bim; Hawley, Adrian; Dong, Yao Da; Boyd, Ben J.

In: Journal of Colloid and Interface Science, Vol. 512, 15.02.2018, p. 369-378.

Research output: Contribution to journalArticleResearchpeer-review

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