Normative performance of healthy older individuals on the Modified Mini-Mental State (3MS) examination according to ethno-racial group, gender, age, and education level

Joanne Ryan, Robyn L. Woods, Carlene Britt, Anne M. Murray, Raj C. Shah, Christopher M. Reid, Brenda Kirpach, Rory S. Wolfe, Mark R. Nelson, Jessica E. Lockery, Suzanne G. Orchard, Ruth E. Trevaks, John J. McNeil, Elsdon Storey, on behalf of the ASPREE Investigator Group

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Objective: To present normative performance data on the Modified Mini-Mental State (3MS) examination for healthy community-dwelling older individuals according to gender, age, education level, and ethno-racial group. Method: More than 19,000 generally healthy older men and women without a diagnosis of dementia were recruited from the general population in Australia and the U.S. for the ASPirin in Reducing Events in the Elderly (ASPREE) study. The 3MS exam was administered as part of the baseline screening and individuals scoring above 77 were eligible to participate. Results: The sample comprised 16,360 Australian whites, 1080 U.S. whites, 895 African-Americans and 316 Hispanic/Latinos. The median age of participants was 74 years (range 65–98), with an average of 12 years of education and 56% were female. Increasing age and fewer years of completed education were associated with lower scores on the 3MS. Women scored higher than men in most age and education categories. Differences across ethno-racial groups were found. With factor analysis, four factors were identified which accounted for 35% of the between-person variance in 3MS scores for white Australians. Conclusions: This large cohort of older individuals provides some of the most comprehensive 3MS normative data to be generated for whites (Australian and U.S.), Hispanic/Latinos and African-Americans, by age, gender, and educational attainment. These findings will serve as important reference standards for monitoring cognitive function in generally healthy older individuals, becoming increasingly important as this fraction of the population increases.

Original languageEnglish
Pages (from-to)779–797
Number of pages19
JournalThe Clinical Neuropsychologist
Volume33
Issue number4
DOIs
Publication statusPublished - 19 May 2019

Keywords

  • aging
  • cognition
  • dementia
  • Modified Mini-Mental Status examination (3MS)
  • normative data
  • Word

Cite this

@article{fc3e602f34b647658e706b851e01b417,
title = "Normative performance of healthy older individuals on the Modified Mini-Mental State (3MS) examination according to ethno-racial group, gender, age, and education level",
abstract = "Objective: To present normative performance data on the Modified Mini-Mental State (3MS) examination for healthy community-dwelling older individuals according to gender, age, education level, and ethno-racial group. Method: More than 19,000 generally healthy older men and women without a diagnosis of dementia were recruited from the general population in Australia and the U.S. for the ASPirin in Reducing Events in the Elderly (ASPREE) study. The 3MS exam was administered as part of the baseline screening and individuals scoring above 77 were eligible to participate. Results: The sample comprised 16,360 Australian whites, 1080 U.S. whites, 895 African-Americans and 316 Hispanic/Latinos. The median age of participants was 74 years (range 65–98), with an average of 12 years of education and 56{\%} were female. Increasing age and fewer years of completed education were associated with lower scores on the 3MS. Women scored higher than men in most age and education categories. Differences across ethno-racial groups were found. With factor analysis, four factors were identified which accounted for 35{\%} of the between-person variance in 3MS scores for white Australians. Conclusions: This large cohort of older individuals provides some of the most comprehensive 3MS normative data to be generated for whites (Australian and U.S.), Hispanic/Latinos and African-Americans, by age, gender, and educational attainment. These findings will serve as important reference standards for monitoring cognitive function in generally healthy older individuals, becoming increasingly important as this fraction of the population increases.",
keywords = "aging, cognition, dementia, Modified Mini-Mental Status examination (3MS), normative data, Word",
author = "Joanne Ryan and Woods, {Robyn L.} and Carlene Britt and Murray, {Anne M.} and Shah, {Raj C.} and Reid, {Christopher M.} and Brenda Kirpach and Wolfe, {Rory S.} and Nelson, {Mark R.} and Lockery, {Jessica E.} and Orchard, {Suzanne G.} and Trevaks, {Ruth E.} and McNeil, {John J.} and Elsdon Storey and {on behalf of the ASPREE Investigator Group}",
year = "2019",
month = "5",
day = "19",
doi = "10.1080/13854046.2018.1488996",
language = "English",
volume = "33",
pages = "779–797",
journal = "The Clinical Neuropsychologist",
issn = "1385-4046",
publisher = "Taylor & Francis",
number = "4",

}

Normative performance of healthy older individuals on the Modified Mini-Mental State (3MS) examination according to ethno-racial group, gender, age, and education level. / Ryan, Joanne; Woods, Robyn L.; Britt, Carlene; Murray, Anne M.; Shah, Raj C.; Reid, Christopher M.; Kirpach, Brenda; Wolfe, Rory S.; Nelson, Mark R.; Lockery, Jessica E.; Orchard, Suzanne G.; Trevaks, Ruth E.; McNeil, John J.; Storey, Elsdon; on behalf of the ASPREE Investigator Group.

In: The Clinical Neuropsychologist, Vol. 33, No. 4, 19.05.2019, p. 779–797.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Normative performance of healthy older individuals on the Modified Mini-Mental State (3MS) examination according to ethno-racial group, gender, age, and education level

AU - Ryan, Joanne

AU - Woods, Robyn L.

AU - Britt, Carlene

AU - Murray, Anne M.

AU - Shah, Raj C.

AU - Reid, Christopher M.

AU - Kirpach, Brenda

AU - Wolfe, Rory S.

AU - Nelson, Mark R.

AU - Lockery, Jessica E.

AU - Orchard, Suzanne G.

AU - Trevaks, Ruth E.

AU - McNeil, John J.

AU - Storey, Elsdon

AU - on behalf of the ASPREE Investigator Group

PY - 2019/5/19

Y1 - 2019/5/19

N2 - Objective: To present normative performance data on the Modified Mini-Mental State (3MS) examination for healthy community-dwelling older individuals according to gender, age, education level, and ethno-racial group. Method: More than 19,000 generally healthy older men and women without a diagnosis of dementia were recruited from the general population in Australia and the U.S. for the ASPirin in Reducing Events in the Elderly (ASPREE) study. The 3MS exam was administered as part of the baseline screening and individuals scoring above 77 were eligible to participate. Results: The sample comprised 16,360 Australian whites, 1080 U.S. whites, 895 African-Americans and 316 Hispanic/Latinos. The median age of participants was 74 years (range 65–98), with an average of 12 years of education and 56% were female. Increasing age and fewer years of completed education were associated with lower scores on the 3MS. Women scored higher than men in most age and education categories. Differences across ethno-racial groups were found. With factor analysis, four factors were identified which accounted for 35% of the between-person variance in 3MS scores for white Australians. Conclusions: This large cohort of older individuals provides some of the most comprehensive 3MS normative data to be generated for whites (Australian and U.S.), Hispanic/Latinos and African-Americans, by age, gender, and educational attainment. These findings will serve as important reference standards for monitoring cognitive function in generally healthy older individuals, becoming increasingly important as this fraction of the population increases.

AB - Objective: To present normative performance data on the Modified Mini-Mental State (3MS) examination for healthy community-dwelling older individuals according to gender, age, education level, and ethno-racial group. Method: More than 19,000 generally healthy older men and women without a diagnosis of dementia were recruited from the general population in Australia and the U.S. for the ASPirin in Reducing Events in the Elderly (ASPREE) study. The 3MS exam was administered as part of the baseline screening and individuals scoring above 77 were eligible to participate. Results: The sample comprised 16,360 Australian whites, 1080 U.S. whites, 895 African-Americans and 316 Hispanic/Latinos. The median age of participants was 74 years (range 65–98), with an average of 12 years of education and 56% were female. Increasing age and fewer years of completed education were associated with lower scores on the 3MS. Women scored higher than men in most age and education categories. Differences across ethno-racial groups were found. With factor analysis, four factors were identified which accounted for 35% of the between-person variance in 3MS scores for white Australians. Conclusions: This large cohort of older individuals provides some of the most comprehensive 3MS normative data to be generated for whites (Australian and U.S.), Hispanic/Latinos and African-Americans, by age, gender, and educational attainment. These findings will serve as important reference standards for monitoring cognitive function in generally healthy older individuals, becoming increasingly important as this fraction of the population increases.

KW - aging

KW - cognition

KW - dementia

KW - Modified Mini-Mental Status examination (3MS)

KW - normative data

KW - Word

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U2 - 10.1080/13854046.2018.1488996

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