Norfloxacin treatment for clinically significant portal hypertension: results of a randomised double-blind placebo-controlled crossover trial

William Wilson Kemp, John Colman, Kenneth Thompson, Anoop Madan, Margaret Vincent, Jaye PF Chin-Dusting, Andrew Richard Kompa, Henry Krum, Stuart Roberts

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)


While selective intestinal decontamination (SID) can alter the hyperdynamic circulatory state of cirrhosis, the impact of SID on portal pressure remains unclear especially in the setting of clinically significant portal hypertension. Aims: To examine the impact of SID with norfloxacin on portal pressure in subjects with clinically significant portal hypertension and explore the potential mechanisms by which norfloxacin exerts its haemodynamic effects
Original languageEnglish
Pages (from-to)427 - 433
Number of pages7
JournalLiver International
Issue number3
Publication statusPublished - 2009

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