Nonquinolone options for the treatment of Mycoplasma genitalium in the era of increased resistance

Michelle Doyle; Lenka A. Vodstrcil; Erica L. Plummer; Ivette Aguirre; Christopher K. Fairley; Catriona S. Bradshaw

doi:10.1093/ofid/ofaa291

Nonquinolone options for the treatment of Mycoplasma genitalium in the era of increased resistance

Research output: Contribution to journal › Article › Research › peer-review

Abstract

In the era of increasing macrolide- and quinolone-resistant Mycoplasma genitalium (MG), we report the efficacy of 2 nonquinolone antimicrobials in patients with limited treatment options. Pristinamycin + doxycycline cured 75% (95% CI, 64%-85%), and minocycline cured 71% (95% CI, 54%-85%) of cases. These data provide useful estimates to inform clinical practice.

Original language	English
Article number	ofaa291
Number of pages	4
Journal	Open Forum Infectious Diseases
Volume	7
Issue number	8
DOIs	https://doi.org/10.1093/ofid/ofaa291
Publication status	Published - Aug 2020

Keywords

Multidrug failure
Mycoplasma genitalium
Sexually transmitted infections
Treatment

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10.1093/ofid/ofaa291Licence: CC BY-NC-ND

Cite this

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title = "Nonquinolone options for the treatment of Mycoplasma genitalium in the era of increased resistance",

abstract = "In the era of increasing macrolide- and quinolone-resistant Mycoplasma genitalium (MG), we report the efficacy of 2 nonquinolone antimicrobials in patients with limited treatment options. Pristinamycin + doxycycline cured 75\% (95\% CI, 64\%-85\%), and minocycline cured 71\% (95\% CI, 54\%-85\%) of cases. These data provide useful estimates to inform clinical practice.",

keywords = "Multidrug failure, Mycoplasma genitalium, Sexually transmitted infections, Treatment",

author = "Michelle Doyle and Vodstrcil, \{Lenka A.\} and Plummer, \{Erica L.\} and Ivette Aguirre and Fairley, \{Christopher K.\} and Bradshaw, \{Catriona S.\}",

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AU - Vodstrcil, Lenka A.

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AU - Aguirre, Ivette

AU - Fairley, Christopher K.

AU - Bradshaw, Catriona S.

PY - 2020/8

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N2 - In the era of increasing macrolide- and quinolone-resistant Mycoplasma genitalium (MG), we report the efficacy of 2 nonquinolone antimicrobials in patients with limited treatment options. Pristinamycin + doxycycline cured 75% (95% CI, 64%-85%), and minocycline cured 71% (95% CI, 54%-85%) of cases. These data provide useful estimates to inform clinical practice.

AB - In the era of increasing macrolide- and quinolone-resistant Mycoplasma genitalium (MG), we report the efficacy of 2 nonquinolone antimicrobials in patients with limited treatment options. Pristinamycin + doxycycline cured 75% (95% CI, 64%-85%), and minocycline cured 71% (95% CI, 54%-85%) of cases. These data provide useful estimates to inform clinical practice.

KW - Multidrug failure

KW - Mycoplasma genitalium

KW - Sexually transmitted infections

KW - Treatment

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Nonquinolone options for the treatment of Mycoplasma genitalium in the era of increased resistance

Abstract

Keywords

Access to Document

Other files and links

Improving treatment and control of drug resistant and refractory sexually transmitted infections

Optimising the control and management of sexually transmitted infections through research and innovation

Cite this

Nonquinolone options for the treatment of Mycoplasma genitalium in the era of increased resistance

Abstract

Keywords

Access to Document

Other files and links

Projects

Improving treatment and control of drug resistant and refractory sexually transmitted infections

Optimising the control and management of sexually transmitted infections through research and innovation

Cite this