Non-injection methods for the production of embryonic stem cell-embryo chimaeras.

S. A. Wood; N. D. Allen; J. Rossant; A. Auerbach; A. Nagy

doi:10.1038/365087a0

Non-injection methods for the production of embryonic stem cell-embryo chimaeras.

S. A. Wood, N. D. Allen, J. Rossant, A. Auerbach, A. Nagy

Research output: Contribution to journal › Article › Research › peer-review

234 Citations (Scopus)

Abstract

The simple aggregation of pluripotent ES cells with morulae-stage embryos can result in viable chimaeras at a similar frequency to that of blastocyst injection. The savings in time and equipment inherent in the aggregation techniques, however, make this approach well worth considering.

Original language	English
Pages (from-to)	87-89
Number of pages	3
Journal	Nature
Volume	365
Issue number	6441
DOIs	https://doi.org/10.1038/365087a0
Publication status	Published - 2 Sept 1993
Externally published	Yes

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title = "Non-injection methods for the production of embryonic stem cell-embryo chimaeras.",

abstract = "The simple aggregation of pluripotent ES cells with morulae-stage embryos can result in viable chimaeras at a similar frequency to that of blastocyst injection. The savings in time and equipment inherent in the aggregation techniques, however, make this approach well worth considering.",

author = "Wood, \{S. A.\} and Allen, \{N. D.\} and J. Rossant and A. Auerbach and A. Nagy",

year = "1993",

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T1 - Non-injection methods for the production of embryonic stem cell-embryo chimaeras.

AU - Wood, S. A.

AU - Allen, N. D.

AU - Rossant, J.

AU - Auerbach, A.

AU - Nagy, A.

PY - 1993/9/2

Y1 - 1993/9/2

N2 - The simple aggregation of pluripotent ES cells with morulae-stage embryos can result in viable chimaeras at a similar frequency to that of blastocyst injection. The savings in time and equipment inherent in the aggregation techniques, however, make this approach well worth considering.

AB - The simple aggregation of pluripotent ES cells with morulae-stage embryos can result in viable chimaeras at a similar frequency to that of blastocyst injection. The savings in time and equipment inherent in the aggregation techniques, however, make this approach well worth considering.

UR - https://www.scopus.com/pages/publications/0027906457

U2 - 10.1038/365087a0

DO - 10.1038/365087a0

M3 - Article

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AN - SCOPUS:0027906457

SN - 0028-0836

VL - 365

SP - 87

EP - 89

JO - Nature

JF - Nature

IS - 6441

ER -

Non-injection methods for the production of embryonic stem cell-embryo chimaeras.

Abstract

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