Non-injection methods for the production of embryonic stem cell-embryo chimaeras.

S. A. Wood, N. D. Allen, J. Rossant, A. Auerbach, A. Nagy

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215 Citations (Scopus)

Abstract

The simple aggregation of pluripotent ES cells with morulae-stage embryos can result in viable chimaeras at a similar frequency to that of blastocyst injection. The savings in time and equipment inherent in the aggregation techniques, however, make this approach well worth considering.

Original languageEnglish
Pages (from-to)87-89
Number of pages3
JournalNature
Volume365
Issue number6441
DOIs
Publication statusPublished - 2 Sep 1993
Externally publishedYes

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