The mammalian host has evolved to develop a diverse array of innate immune receptors and strategies to defend itself against infection by microbial pathogens. These germ-line-encoded and conserved microbial receptors, called pattern recognition receptors (PRRs), are associated with the membranes or within the cytosol of host cells. PRRs enable the host to rapidly respond to pathogen-associated molecular patterns (PAMPs), as a first line of defence against microbial intrusion.
|Title of host publication||Molecular Genetics of Inflammatory Bowel Disease|
|Editors||Mario D'Amato, John D Rioux|
|Place of Publication||New York, United States|
|Pages||191 - 217|
|Number of pages||27|
|Publication status||Published - 2013|