Nod1 and Nod2 and the immune response to bacteria

Maria Liaskos; Dana Philpott

doi:10.1007/978-1-4614-8256-7_10

Nod1 and Nod2 and the immune response to bacteria

Maria Liaskos, Dana Philpott

Hudson Institute - Centre for Innate Immunity and Infectious Disease

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other

Abstract

The mammalian host has evolved to develop a diverse array of innate immune receptors and strategies to defend itself against infection by microbial pathogens. These germ-line-encoded and conserved microbial receptors, called pattern recognition receptors (PRRs), are associated with the membranes or within the cytosol of host cells. PRRs enable the host to rapidly respond to pathogen-associated molecular patterns (PAMPs), as a first line of defence against microbial intrusion.

Original language	English
Title of host publication	Molecular Genetics of Inflammatory Bowel Disease
Editors	Mario D'Amato, John D Rioux
Place of Publication	New York, United States
Publisher	Springer
Pages	191 - 217
Number of pages	27
ISBN (Print)	9781461482550
DOIs	https://doi.org/10.1007/978-1-4614-8256-7_10
Publication status	Published - 2013

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10.1007/978-1-4614-8256-7_10

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Nod1 and Nod2 and the immune response to bacteria

Abstract

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