Nocturnal dipping is preserved in children with sleep disordered breathing regardless of its severity

Rosemary Sylvia Claire Horne, Shao-Chung Joel Yang, Lisa Mary Walter, Heidi Louise Richardson, Denise Marie O'Driscoll, Alison M Foster, Shi Wong, Michelle L Ng, Farhat Bashir, Ruth Rebecca Patterson, Damien Jolley, Adrian Mark Walker, Vicki Anne Anderson, Margot J Davey, Gillian Michelle Nixon

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15 Citations (Scopus)

Abstract

Sleep disordered breathing (SDB) in adults has been associated with a loss of nocturnal dipping in blood pressure (BP) and heart rate, however, there have been limited studies in children. We measured BP non-invasively and continuously overnight in 105 children aged 7-12 with a range of severities of SDB and 36 non-snoring controls to examine nocturnal dipping profiles. STUDY DESIGN: Children with SDB were divided into three severity groups according to their obstructive apnea hypopnea index. Nocturnal dipping profiles across sleep stages were described both as a proportion of children exhibiting a >/=10 fall in systolic arterial pressure (SAP) and heart rate (HR) from wake to sleep and according to SAP sleep/SAP wake ratio as extreme dippers (ratio 1.0). RESULTS: The mean fall in BP between wake and NREM 1/2, SWS, and REM sleep was not different between the groups and there were no differences between the dipping profiles of children in each group. CONCLUSIONS: SDB did not alter nocturnal dipping patterns of BP and HR compared to controls, a finding which may suggest that these young children have not been exposed to the effects of SDB long enough or that SDB severity was not great enough to affect nocturnal dipping profiles. However, further studies are required to determine if the elevated BP previously reported in this group of children will have long-term effects on the cardiovascular system. Pediatr Pulmonol. 2013; 48:1127-1134. (c) 2013 Wiley Periodicals, Inc.
Original languageEnglish
Pages (from-to)1127 - 1134
Number of pages8
JournalPediatric Pulmonology
Volume48
Issue number11
DOIs
Publication statusPublished - 2013

Cite this

Horne, Rosemary Sylvia Claire ; Yang, Shao-Chung Joel ; Walter, Lisa Mary ; Richardson, Heidi Louise ; O'Driscoll, Denise Marie ; Foster, Alison M ; Wong, Shi ; Ng, Michelle L ; Bashir, Farhat ; Patterson, Ruth Rebecca ; Jolley, Damien ; Walker, Adrian Mark ; Anderson, Vicki Anne ; Davey, Margot J ; Nixon, Gillian Michelle. / Nocturnal dipping is preserved in children with sleep disordered breathing regardless of its severity. In: Pediatric Pulmonology. 2013 ; Vol. 48, No. 11. pp. 1127 - 1134.
@article{13ea8982f99b471d8ec6a2fd19753e87,
title = "Nocturnal dipping is preserved in children with sleep disordered breathing regardless of its severity",
abstract = "Sleep disordered breathing (SDB) in adults has been associated with a loss of nocturnal dipping in blood pressure (BP) and heart rate, however, there have been limited studies in children. We measured BP non-invasively and continuously overnight in 105 children aged 7-12 with a range of severities of SDB and 36 non-snoring controls to examine nocturnal dipping profiles. STUDY DESIGN: Children with SDB were divided into three severity groups according to their obstructive apnea hypopnea index. Nocturnal dipping profiles across sleep stages were described both as a proportion of children exhibiting a >/=10 fall in systolic arterial pressure (SAP) and heart rate (HR) from wake to sleep and according to SAP sleep/SAP wake ratio as extreme dippers (ratio 1.0). RESULTS: The mean fall in BP between wake and NREM 1/2, SWS, and REM sleep was not different between the groups and there were no differences between the dipping profiles of children in each group. CONCLUSIONS: SDB did not alter nocturnal dipping patterns of BP and HR compared to controls, a finding which may suggest that these young children have not been exposed to the effects of SDB long enough or that SDB severity was not great enough to affect nocturnal dipping profiles. However, further studies are required to determine if the elevated BP previously reported in this group of children will have long-term effects on the cardiovascular system. Pediatr Pulmonol. 2013; 48:1127-1134. (c) 2013 Wiley Periodicals, Inc.",
author = "Horne, {Rosemary Sylvia Claire} and Yang, {Shao-Chung Joel} and Walter, {Lisa Mary} and Richardson, {Heidi Louise} and O'Driscoll, {Denise Marie} and Foster, {Alison M} and Shi Wong and Ng, {Michelle L} and Farhat Bashir and Patterson, {Ruth Rebecca} and Damien Jolley and Walker, {Adrian Mark} and Anderson, {Vicki Anne} and Davey, {Margot J} and Nixon, {Gillian Michelle}",
year = "2013",
doi = "10.1002/ppul.22727",
language = "English",
volume = "48",
pages = "1127 -- 1134",
journal = "Pediatric Pulmonology",
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Horne, RSC, Yang, S-CJ, Walter, LM, Richardson, HL, O'Driscoll, DM, Foster, AM, Wong, S, Ng, ML, Bashir, F, Patterson, RR, Jolley, D, Walker, AM, Anderson, VA, Davey, MJ & Nixon, GM 2013, 'Nocturnal dipping is preserved in children with sleep disordered breathing regardless of its severity', Pediatric Pulmonology, vol. 48, no. 11, pp. 1127 - 1134. https://doi.org/10.1002/ppul.22727

Nocturnal dipping is preserved in children with sleep disordered breathing regardless of its severity. / Horne, Rosemary Sylvia Claire; Yang, Shao-Chung Joel; Walter, Lisa Mary; Richardson, Heidi Louise; O'Driscoll, Denise Marie; Foster, Alison M; Wong, Shi; Ng, Michelle L; Bashir, Farhat; Patterson, Ruth Rebecca; Jolley, Damien; Walker, Adrian Mark; Anderson, Vicki Anne; Davey, Margot J; Nixon, Gillian Michelle.

In: Pediatric Pulmonology, Vol. 48, No. 11, 2013, p. 1127 - 1134.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Nocturnal dipping is preserved in children with sleep disordered breathing regardless of its severity

AU - Horne, Rosemary Sylvia Claire

AU - Yang, Shao-Chung Joel

AU - Walter, Lisa Mary

AU - Richardson, Heidi Louise

AU - O'Driscoll, Denise Marie

AU - Foster, Alison M

AU - Wong, Shi

AU - Ng, Michelle L

AU - Bashir, Farhat

AU - Patterson, Ruth Rebecca

AU - Jolley, Damien

AU - Walker, Adrian Mark

AU - Anderson, Vicki Anne

AU - Davey, Margot J

AU - Nixon, Gillian Michelle

PY - 2013

Y1 - 2013

N2 - Sleep disordered breathing (SDB) in adults has been associated with a loss of nocturnal dipping in blood pressure (BP) and heart rate, however, there have been limited studies in children. We measured BP non-invasively and continuously overnight in 105 children aged 7-12 with a range of severities of SDB and 36 non-snoring controls to examine nocturnal dipping profiles. STUDY DESIGN: Children with SDB were divided into three severity groups according to their obstructive apnea hypopnea index. Nocturnal dipping profiles across sleep stages were described both as a proportion of children exhibiting a >/=10 fall in systolic arterial pressure (SAP) and heart rate (HR) from wake to sleep and according to SAP sleep/SAP wake ratio as extreme dippers (ratio 1.0). RESULTS: The mean fall in BP between wake and NREM 1/2, SWS, and REM sleep was not different between the groups and there were no differences between the dipping profiles of children in each group. CONCLUSIONS: SDB did not alter nocturnal dipping patterns of BP and HR compared to controls, a finding which may suggest that these young children have not been exposed to the effects of SDB long enough or that SDB severity was not great enough to affect nocturnal dipping profiles. However, further studies are required to determine if the elevated BP previously reported in this group of children will have long-term effects on the cardiovascular system. Pediatr Pulmonol. 2013; 48:1127-1134. (c) 2013 Wiley Periodicals, Inc.

AB - Sleep disordered breathing (SDB) in adults has been associated with a loss of nocturnal dipping in blood pressure (BP) and heart rate, however, there have been limited studies in children. We measured BP non-invasively and continuously overnight in 105 children aged 7-12 with a range of severities of SDB and 36 non-snoring controls to examine nocturnal dipping profiles. STUDY DESIGN: Children with SDB were divided into three severity groups according to their obstructive apnea hypopnea index. Nocturnal dipping profiles across sleep stages were described both as a proportion of children exhibiting a >/=10 fall in systolic arterial pressure (SAP) and heart rate (HR) from wake to sleep and according to SAP sleep/SAP wake ratio as extreme dippers (ratio 1.0). RESULTS: The mean fall in BP between wake and NREM 1/2, SWS, and REM sleep was not different between the groups and there were no differences between the dipping profiles of children in each group. CONCLUSIONS: SDB did not alter nocturnal dipping patterns of BP and HR compared to controls, a finding which may suggest that these young children have not been exposed to the effects of SDB long enough or that SDB severity was not great enough to affect nocturnal dipping profiles. However, further studies are required to determine if the elevated BP previously reported in this group of children will have long-term effects on the cardiovascular system. Pediatr Pulmonol. 2013; 48:1127-1134. (c) 2013 Wiley Periodicals, Inc.

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U2 - 10.1002/ppul.22727

DO - 10.1002/ppul.22727

M3 - Article

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