No increased risk of mothers of children with autism having androgen-related cancers in an Australian population based sample

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Background: Some past studies have suggested a link between autism spectrum disorder (ASD) and testosterone related cancers. This study explored androgen-related cancer in mothers of children with and without parent-reported ASD in a prospective Australian population based sample. Methods: Odds of self-reported breast, uterine and cervical cancer in mothers of children with and without parent-reported ASD in the Longitudinal Study of Australian Children. This prospective population based study contains two cohorts of children recruited at birth or 4 years of age. Results: Of 324 children with parent-reported ASD and 6,948 without, there were no significantly increased odds for children with ASD and mother breast (AOR 1.20 [95 % CI.50, 2.87]), uterine (AOR.92 [95 % CI.05, 15.78]), cervical (AOR 1.23 [95% CI.46, 3.25]) or all cancers (AOR 1.13 [95% CI.58, 2.21]). Conclusions: This study found no evidence to support an increased or decreased androgen related cancer risk in mothers of children with parent-reported ASD.

Original languageEnglish
Article number101858
Number of pages6
JournalResearch in Autism Spectrum Disorders
Publication statusPublished - Oct 2021


  • Autism spectrum disorder
  • Cancer
  • Longitudinal study of Australian children

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