No association between the Eczema genes COL29A1 and IL31 and inflammatory bowel disease

Marco Zucchelli, Leif Torkvist, Francesca Bresso, Jonas Halfvarson, Cilla Söderhäll, Young Ae Lee, Robert Löfberg, Juha Kere, Mauro D'Amato

Research output: Contribution to journalLetterOtherpeer-review

3 Citations (Scopus)

Abstract

Common genes and pathways have been discovered that affect individual predisposition to inflammatory diseases of the barrier organs such as asthma, eczema, psoriasis, and the inflammatory bowel diseases (IBDs), Crohn's disease (CD) and ulcerative colitis (UC).1 The underlying common pathogenetic mechanisms appear to involve a breakdown of the epithelial barrier (in the lungs, skin, or intestine), which leads to increased exposure to environmental stimuli (for instance, bacteria and allergens), and consequent dysregulation of the immune response in predisposed individuals.2
Original languageEnglish
Pages (from-to)961-962
Number of pages2
JournalInflammatory Bowel Diseases
Volume15
Issue number7
DOIs
Publication statusPublished - 18 Sept 2009
Externally publishedYes

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