Abstract
Clinical trials studying age of transfused red blood cells (RBCs) have found no evidence of benefit from transfusion of fresher RBCs. However, these studies have not included patients requiring massive transfusion for major bleeding, a patient population that may be more susceptible to adverse effects of the RBC storage lesion. Further, no clinical trials have specifically evaluated the safety of transfusing RBCs approaching expiry (30-42 days). We investigated the association between RBC storage time and 30-day mortality in a large cohort of massively transfused patients (5 RBCs within 4 hours, from any bleeding context).
Original language | English |
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Article number | 3728 |
Number of pages | 1 |
Journal | Blood |
Volume | 130 |
Issue number | Suppl 1 |
Publication status | Published - 2017 |
Keywords
- Blood
- Red cells
- red cell transfusion
- intensive care
- REGISTRY