Nitrofurantoin and fosfomycin for resistant urinary tract infections

old drugs for emerging problems

Research output: Contribution to journalArticleOtherpeer-review

Abstract

Uncomplicated urinary tract infection is one of the most common indications for antibiotic use in the community. However, the Gram-negative organisms that can cause the infection are becoming more resistant to antibiotics
Many multidrug resistant organisms retain susceptibility to two old antibiotics, nitrofurantoin and fosfomycin. Advantages over newer drugs include their high urinary concentrations and minimal toxicity
Fosfomycin is a potential treatment option for patients with uncomplicated urinary tract infection due to resistant organisms. Nitrofurantoin may be more effective and can be used for urinary infections in pregnant women
Original languageEnglish
Pages (from-to)14-19
Number of pages6
JournalAustralian Prescriber
Volume42
Issue number1
DOIs
Publication statusPublished - 1 Feb 2019

Cite this

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title = "Nitrofurantoin and fosfomycin for resistant urinary tract infections: old drugs for emerging problems",
abstract = "Uncomplicated urinary tract infection is one of the most common indications for antibiotic use in the community. However, the Gram-negative organisms that can cause the infection are becoming more resistant to antibioticsMany multidrug resistant organisms retain susceptibility to two old antibiotics, nitrofurantoin and fosfomycin. Advantages over newer drugs include their high urinary concentrations and minimal toxicityFosfomycin is a potential treatment option for patients with uncomplicated urinary tract infection due to resistant organisms. Nitrofurantoin may be more effective and can be used for urinary infections in pregnant women",
author = "Gardiner, {Bradley J} and Stewardson, {Andrew J} and Abbott, {Iain J.} and Peleg, {Anton Y.}",
year = "2019",
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doi = "10.18773/austprescr.2019.002",
language = "English",
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Nitrofurantoin and fosfomycin for resistant urinary tract infections : old drugs for emerging problems. / Gardiner, Bradley J; Stewardson, Andrew J; Abbott, Iain J.; Peleg, Anton Y.

In: Australian Prescriber, Vol. 42, No. 1, 01.02.2019, p. 14-19.

Research output: Contribution to journalArticleOtherpeer-review

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AB - Uncomplicated urinary tract infection is one of the most common indications for antibiotic use in the community. However, the Gram-negative organisms that can cause the infection are becoming more resistant to antibioticsMany multidrug resistant organisms retain susceptibility to two old antibiotics, nitrofurantoin and fosfomycin. Advantages over newer drugs include their high urinary concentrations and minimal toxicityFosfomycin is a potential treatment option for patients with uncomplicated urinary tract infection due to resistant organisms. Nitrofurantoin may be more effective and can be used for urinary infections in pregnant women

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DO - 10.18773/austprescr.2019.002

M3 - Article

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