NF-k(kappa)B subunit specificity in hemopoiesis.

Steven Demetrious Gerondakis, Ashish Banerjee, George Grigoriadis, Ajithkumar Vasanthakumar, Raffi Gugasyan, Tom Sidwell, Raelene Joy Grumont

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Although the diverse functions served by the nuclear factor-I?B (NF-I?B) pathway in virtually all cell types are typically employed to deal with stress responses, NF-I?B transcription factors also play key roles in the development of hemopoietic cells. This review focuses on how NF-I?B transcription factors control various aspects of thymic T-cell and myeloid cell differentiation that include its roles in hemopoietic precursors, conventional I?I? T cells, CD4 + regulatory T cells, natural killer T cells, I?I T cells, macrophages, and dendritic cells. A? 2012 John Wiley Sons A/S.
Original languageEnglish
Pages (from-to)272 - 285
Number of pages14
JournalImmunological Reviews
Volume246
Issue number1
DOIs
Publication statusPublished - 2012

Cite this

Gerondakis, Steven Demetrious ; Banerjee, Ashish ; Grigoriadis, George ; Vasanthakumar, Ajithkumar ; Gugasyan, Raffi ; Sidwell, Tom ; Grumont, Raelene Joy. / NF-k(kappa)B subunit specificity in hemopoiesis. In: Immunological Reviews. 2012 ; Vol. 246, No. 1. pp. 272 - 285.
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NF-k(kappa)B subunit specificity in hemopoiesis. / Gerondakis, Steven Demetrious; Banerjee, Ashish; Grigoriadis, George; Vasanthakumar, Ajithkumar; Gugasyan, Raffi; Sidwell, Tom; Grumont, Raelene Joy.

In: Immunological Reviews, Vol. 246, No. 1, 2012, p. 272 - 285.

Research output: Contribution to journalArticleResearchpeer-review

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